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CXCL10信息

英文名称:C-X-C motif chemokine ligand 10
中文名称:C-X-C基序趋化因子配体10
靶点别称:Protein 10 From Interferon (Gamma)-Induced Cell Line,CXCL10,INP10,SCYB10,C-X-C motif chemokine 10,10 kDa interferon gamma-induced protein,IP-10,C-X-C Motif Chemokine Ligand 10,Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 10,Chemokine (C-X-C Motif) Ligand 10,Small-Inducible Cytokine B10,Chemokine CXCL10,Interferon-Inducible Cytokine IP-10,Gamma IP10,Gamma-IP10,GIP-10,IFI10,Crg-2,Mob-1,C7
上市药物数量:0
临床药物数量:3
最高研发阶段:临床二期

CXCL10产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
CX0-H52H9
Human
Unconjugated,CXCL10,Human,His,HEK
 
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CXCL10 分子别名

C-X-C motif chemokine 10,10 kDa interferon gamma-induced protein,Gamma-IP10,IP-10,Small-inducible cytokine B10,CXCL10(1-73),CXCL10,INP10, SCYB10

CXCL10 分子背景

C-X-C Motif Chemokine Ligand 10 (CXCL10) is a pro-inflammatory chemokine secreted by a wide spectrum of cells. It is involved in multiple mechanisms and reported to have pleiotropic effects, including immune cell migration and attraction to inflammation sites, angiogenesis, and cancer cell growth. CXCL10 is produced by pancreatic islet cells upon inflammatory stress and is specifically recognized by C-X-C Motif Chemokine Receptor 3 (CXCR3) which is expressed by activated T-lymphocytes and other immune cells.

CXCL10 前沿进展

CXCL10临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
JT-02 (JYANT Technologies) JT-02 临床二期 Jyant Technologies 炎症性肠疾病 详情
Eldelumab MDX-1100; BMS-936557 百时美施贵宝, Medarex 详情
NI-0801 Alpha-IP-10; NI-0801; α-IP-10 Novimmune 详情
NG-641 NG-641; NG-aFAP; EnAd-FAP-Tac; EnAd-FAP-BiTE 临床一期 牛津大学, Psioxus Therapeutics Ltd 头颈部鳞状细胞癌, 腺性和上皮性肿瘤, 转移癌 详情

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