登录 | 注册    关注公众号  
搜索

IL-10 R alpha产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
ILR-H82F6
Human
Biotinylated Human IL-10 R alpha / CD210 Protein, Fc,Avitag™ (MALS verified)
 
评论(0)
 

IL-10 R alpha 分子别名

Interleukin-10 receptor subunit alpha,IL-10 receptor subunit alpha,IL-10R subunit alpha,IL-10RA,CDw210a,Interleukin-10 receptor subunit 1,IL-10R subunit 1,IL-10R1,CD210,IL10RA,IL10R

IL-10 R alpha 分子背景

Interleukin-10 receptor subunit alpha (IL-10 R alpha ) is a cell surface receptor for the cytokine IL-10 that participates in IL-10 mediated anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Upon binding to IL10, induces a conformational change in IL10RB, allowing IL10RB to bind IL10 as well.In turn, the heterotetrameric assembly complex, composed of two subunits of IL10RA and IL10RB, activates the kinases JAK1 and TYK2 that are constitutively associated with IL10RA and IL10RB respectively.These kinases then phosphorylate specific tyrosine residues in the intracellular domain in IL10RA leading to the recruitment and subsequent phosphorylation of STAT3.

IL-10 R alpha 前沿进展

消息提示

请输入您的联系方式,再点击提交!

确定