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Angiopoietin-like 4信息

英文名称:Angiopoietin-related protein 4
中文名称:血管生成素相关蛋白4
靶点别称:Angiopoietin-like protein 4,Hepatic fibrinogen/angiopoietin-related protein,HFARP,ARP4,PGAR,PP1158,PSEC0166,UNQ171/PRO197,Angiopoietin Like 4,Hepatic Fibrinogen/Angiopoietin-Related Protein,Angiopoietin-Related Protein 4,Pp1158,FIAF,NL2,Peroxisome Proliferator-Activated Receptor (PPAR) Gamma Induced Angiopoietin-Related Protein,Hepatic Angiopoietin-Related Protein,PPARG Angiopoietin Related Protein,Fasting-Induced Adipose Factor,Angiopoietin-Like Protein 4,Angiopoietin-Like 4,UNQ171,TGQTL,HARP
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

Angiopoietin-like 4产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
AN4-H5243
Human
Human Angiopoietin-like 4 / ANGPTL4 (166-406) Protein, His Tag
ACRO质量管理体系
 
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Angiopoietin-like 4 分子别名

ANGPTL4,ANGPTL2,ARP4,FIAF,HFARP,NL2,PGAR,pp1158,Angiopoietin like 4

Angiopoietin-like 4 分子背景

Angiopoietin-related protein 4 (ANGPTL4) is also known as Hepatic fibrinogen / angiopoietin - related protein (HFARP), ARP4, PGAR. ANGPTL4 contains one fibrinogen C-terminal domain. ANGPTL4 is a homooligomer , and the homooligomer undergoes proteolytic processing to release its carboxyl fibrinogen-like domain, which circulates as a monomer. The homooligomer unprocessed form is able to interact with the extracellular matrix. ANGPTL4 may act as a regulator of angiogenesis and modulate tumorigenesis. ANGPTL4 inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action.

Angiopoietin-like 4 前沿进展

Angiopoietin-like 4临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Lipisense 临床一期 Lipigon Pharmaceuticals AB, Secarna Pharmaceuticals GmbH & Co KG 高甘油三酯血症 详情

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