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Midkine信息

英文名称:Midkine
中文名称:中期因子
靶点别称:Midkine,Midgestation and kidney protein,Neurite outgrowth-promoting factor 2,Neurite outgrowth-promoting protein,Amphiregulin-associated protein,NEGF2,ARAP,FLJ27379,Neurite Growth-Promoting Factor 2,Retinoic Acid Inducible Factor,MK1,MDK,MK
上市药物数量:0
临床药物数量:1
最高研发阶段:临床阶段不明

Midkine 分子别名

MDK,MEK,Midkine,MK1,MKARAP,NEGF2,Retinoic acid-induced differentiation factor

Midkine 分子背景

Secreted protein that functions as cytokine and growth factor and mediates its signal through cell-surface proteoglycan and non-proteoglycan receptors.Binds cell-surface proteoglycan receptors via their chondroitin sulfate (CS) groups.Thereby regulates many processes like inflammatory response, cell proliferation, cell adhesion, cell growth, cell survival, tissue regeneration, cell differentiation and cell migration. Participates in inflammatory processes by exerting two different activities. Firstly, mediates neutrophils and macrophages recruitment to the sites of inflammation both by direct action by cooperating namely with ITGB2 via LRP1 and by inducing chemokine expression.

Midkine 前沿进展

Midkine临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
CMK-103 CMK-103 临床阶段不明 Cellmid 心肌梗塞 详情

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