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CXCL13信息

英文名称:C-X-C motif chemokine 13
中文名称:C-C基序趋化因子-13
靶点别称:BCA-1,B cell-attracting chemokine 1
上市药物数量:0
临床药物数量:0
最高研发阶段:临床前

CXCL13产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
CX3-H5249
Human
Human CXCL13 / BCA-1 Protein, His Tag
 
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CXCL13 分子别名

C-X-C motif chemokine 13,Angie,B cell-attracting chemokine 1,BCA-1,B lymphocyte chemoattractant,CXC chemokine BLC,Small-inducible cytokine B13,CXCL13,BCA1,BLC,SCYB13

CXCL13 分子背景

CXCL13, originally known as BLC (B-lymphocyte chemoattractant) or BCA-1 (B cell-attracting chemokine 1), is a homeostatic chemokine. It is constitutively secreted by stromal cells in B-cell areas of secondary lymphoid tissues (follicles), such as spleen, lymph nodes, tonsils, and Peyer's patches. CXCL13 plays a key role in orchestrating cell migration within spatially distinct regions of the secondary lymphoid organs. It strongly attracts B lymphocytes while promoting migration of only small numbers of T cells and macrophages. CXCL13 exerts its functions through its receptor CXCR5, which initially, was isolated from Burkitt Lymphoma and therefore designated as Burkitt's lymphoma receptor 1 (BLR1).

CXCL13 前沿进展

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