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ADAM9产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
AD9-H52H7
Human
Human ADAM9 Protein, His Tag
AD9-C52H7
Cynomolgus
Cynomolgus ADAM9 Protein, His Tag
 
评论(1)
AD9-C52H7|Cynomolgus ADAM9 Protein, His Tag
  1. 136XXXXXXX5
  2. 1人赞
  3. 长期老顾客,买了无数次了,多种高质量蛋白,用于linker实验,得到了很好的研究,满足抗体制备.希望一直保持下去
  4. 2022-06-17
 

ADAM9 分子别名

Disintegrin and metalloproteinase domain-containing protein 9 (EC:3.4.24.-)Cellular disintegrin-related protein,Meltrin-gamma,Metalloprotease/disintegrin/cysteine-rich protein 9,Myeloma cell metalloproteinase,ADAM9,KIAA0021, MCMP, MDC9, MLTNG

ADAM9 分子背景

ADAM9 (A disintegrin and a metalloprotease 9) is a membrane-anchored protein that participates in a variety of physiological functions, primarily through the disintegrin domain for adhesion and the metalloprotease domain for ectodomain shedding of a wide variety of cell surface proteins. ADAM9 influences the developmental process, inflammation, and degenerative diseases.Recently, increasing evidence has shown that ADAM9 plays an important role in tumor biology. Overexpression of ADAM9 has been found in several cancer types and is correlated with tumoraggressiveness and poor prognosis. In addition, through either proteolytic or non-proteolytic pathways, ADAM9 promotes tumor progression, therapeutic resistance, and metastasis of cancers.Therefore, comprehensively understanding the mechanism of ADAM9 is crucial for the development of therapeutic anti-cancer strategies. In this review, we summarize the current understanding of ADAM9 in biological function, pathophysiological diseases, and various cancers. Recent advances in therapeutic strategies using ADAM9-related pathways are presented as well.

ADAM9 前沿进展

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