NFAT 靶点蛋白|抗体药物|临床药物信息

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货号	物种	产品描述	蛋白结构	纯度	活性
CHEK-ATF050	Human	NFAT (Luc) HEK293 Reporter Cell
SCJUR-STF046	Human	NFAT (Luc) Jurkat Reporter Cell Development Service

NFAT 分子别名

NFAT

NFAT 分子背景

Nuclear factor of activated T cells (NFAT), which is the pharmacological target of immunosuppressants cyclosporine and tacrolimus, has been shown to play an important role in T cells (immune system) and many biological events. Accumulating studies have indicated that NFATs are involved in many aspects of cancer, including carcinogenesis, cancer cell proliferation, invasion, metastasis, angiogenesis, drug resistance and tumor microenvironment. As the key section of the adaptive immune response, the T cell receptor (TCR)-calcium-calcineurin signaling pathway could lead to T cell activation. The 'nuclear factor of activated T cells' proteins are transcription factors that promote expression of a panel of genes required for activation.

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