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NFAT产品列表

产品库
物种
属性
货号 物种 产品描述 蛋白结构 纯度 活性
CHEK-ATF050
Human
NFAT (Luc) HEK293 Reporter Cell
CJUR-STF046
Human
NFAT (Luc) Jurkat Reporter Cell
 
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NFAT 分子别名

NFAT

NFAT 分子背景

Nuclear factor of activated T cells (NFAT), which is the pharmacological target of immunosuppressants cyclosporine and tacrolimus, has been shown to play an important role in T cells (immune system) and many biological events. Accumulating studies have indicated that NFATs are involved in many aspects of cancer, including carcinogenesis, cancer cell proliferation, invasion, metastasis, angiogenesis, drug resistance and tumor microenvironment. As the key section of the adaptive immune response, the T cell receptor (TCR)-calcium-calcineurin signaling pathway could lead to T cell activation. The 'nuclear factor of activated T cells' proteins are transcription factors that promote expression of a panel of genes required for activation.

NFAT 前沿进展

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