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Activin RIIA产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
ACA-H5269
Human
Human Activin RIIA / ACVR2A Protein, Fc Tag
 
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Activin RIIA 分子别名

Activin receptor type IIA,ACTRIIA

Activin RIIA 分子背景

Activin receptor type-2A (ACVR2A) is also known as Activin receptor type IIA, ACTR-IIA, ACTRIIA and ACVR2,which is single-pass type I membrane protein. ACVR2A belongs to the protein kinase superfamily,TKL Ser/Thr protein kinase family and TGFB receptor subfamily.On ligand binding,ACVR2A can forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.ACVR2A is Receptor for activin A, activin B and inhibin A as well. Several type I I activin receptors have been identified and bind to different activins with different affinities.

Activin RIIA 前沿进展

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