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Star Staining
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Fusion glycoprotein F0产品列表
产品库
标签
属性
| 货号 | 物种 | 产品描述 | 蛋白结构 | 纯度 | 活性 |
|---|---|---|---|---|---|
| RSF-V52H6 |
Human respiratory syncytial virus A (strain A2) |
HRSV (A) Post-fusion glycoprotein F0, His Tag (MALS verified) |
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| RSF-V52H7 |
Human respiratory syncytial virus A (strain A2) |
HRSV (A) Pre-fusion glycoprotein F0, His Tag |
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Fusion glycoprotein F0 分子别名
Fusion glycoprotein F0
Fusion glycoprotein F0 分子背景
Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. The RSV fusion glycoprotein (RSV F) is the principal target of RSV neutralizing antibodies in human sera. The RSV F is a type I viral fusion protein synthesized as inactive, single-chain polypeptides that assemble into trimers. RSV F fuses the viral and host cell membranes by irreversible protein refolding from the labile prefusion conformation to the stable post-fusion conformation. Both states exhibit epitopes targeted by neutralizing antibodies, and post-fusion RSV F is being developed as a vaccine candidate.
