SpeB 靶点蛋白|抗体药物|临床药物信息 - ACROBiosystems中国

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在线 (1)

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Streptococcus pyogenes (1)

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Protein (1)

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Unconjugated (1)

货号	物种	产品描述	蛋白结构	纯度	活性
SPB-S5115	Streptococcus pyogenes	SpeB (40U/μl)

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SpeB分子别名

Streptopain,Exotoxin type B,Streptococcal cysteine proteinase

SpeB分子背景

SpeB is derived from Streptococcus pyogenes. It is an important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. It also cleaves human IL1B precursor to form biologically active IL1B and can induce apoptosis in human monocytes and epithelial cells in vitro, reduces phagocytic activity in monocytic cells. Thus, it may play a role in bacterial colonization, invasion, and inhibition of wound healing.

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