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CLEC5A产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
CLA-H5243
Human
Human CLEC5A / MDL-1 Protein, His Tag (MALS & SPR verified)
ACRO质量管理体系
 
评论(1)
CLA-H5243|Human CLEC5A / MDL-1 Protein, His Tag (MALS & SPR verified)
  1. 156XXXXXXX8
  2. 3人赞
  3. 我们采购人的CLEC5A蛋白主要是用于动物免疫,用于抗体筛选工作。蛋白经过SDS-PAGE检测纯度很高,能够到达小鼠免疫的要求,目前用于动物免疫工作,后期还将用于阳性杂交瘤细胞株的筛选.
  4. 2022-04-06
 

CLEC5A分子别名

CLEC5A,CLECSF5,superfamilymember 5,C-type lectin domain family 5, member A,MDL1,MDL-1,DAP12-associating lectin 1

CLEC5A分子背景

CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily.CLEC5A is expressed on monocytes, macrophages, and neutrophils. Its expression is up-regulated on monocytes in rheumatoid arthritis. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.

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