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DR3 / TNFRSF25信息

英文名称:Tumor necrosis factor receptor superfamily member 25
中文名称:肿瘤坏死因子受体超家族成员25
靶点别称:Apo-3,Apoptosis-inducing receptor AIR,Apoptosis-mediating receptor DR3,Apoptosis-mediating receptor TRAMP,Death receptor 3,Lymphocyte-associated receptor of death,Protein WSL,DDR3,Death Receptor Beta,TNFRSF12,TRAMP,DR3,WSL-1,PH Domain-Containing Family G Member 5,PLEKHG5,WSL-LR,WSL1,APO3,WSL,TR3,TNF Receptor Superfamily Member 25,Death Domain Receptor 3 Soluble Form,GEF720,Guanine Nucleotide Exchange Factor 720,Apoptosis Inducing Receptor,Tumor Necrosis Factor Receptor Superfamily, Member 25,Ple
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

DR3 / TNFRSF25产品列表

 
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DR3 / TNFRSF25 分子别名

TNFRSF25,DR3,APO3,DDR3,TNFRSF12,WSL,WSL1

DR3 / TNFRSF25 分子背景

Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily. TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.

DR3 / TNFRSF25 前沿进展

DR3 / TNFRSF25临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
PTX-35 PTX-35 临床一期 Heat Biologics 实体瘤 详情

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