This product worked great in our ELISA based screening assay. We were having trouble with the assay, but by using this product we were able to get the expected result. The bioactivity data provided was very helpful in determining the amount of laminin 511 E8 Fc to use in the assay. The ELISA protocol provided was very helpful as well. We edited our ELISA based protocol based on the information provided and the assay worked perfectly the first time.
2022-08-16
Laminin 511 E8 分子别名
Laminin 511 E8, LN-511-E8, Laminin-511 E8
Laminin 511 E8 分子背景
Laminin 511 E8 is a truncated laminin 511, which is one of the ECM proteins. laminin E8s serve as functionally minimal forms that retain the full capability for binding to integrins. Laminin 511-E8 consists of the C-terminal end of the alpha 5, beta 1, and gamma 1 chains. The laminin-511 heterotrimer (α5β1γ1) is one of the isoforms to be identified and a potent adhesive and pro-migratory substrate for a variety of normal and tumor cell lines in vitro. Previous studies indicated that laminin-511 contributes to tumor dissemination and metastasis in advanced breast carcinomas and other tumor types. Additionally, latest research uncovered that Laminin 511 might be a target antigen and involved in autoimmune pancreatitis.
膜杰作
Star Staining
Aneuro
ComboX
ActiveMax
GENPower
ClinMax
Star Ribbon
