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Laminin 511 E8产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
LA8-H5283
Human
Human Laminin 511 E8 Protein, Fc Tag
 
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Laminin 511 E8 分子别名

Laminin 511 E8, LN-511-E8, Laminin-511 E8

Laminin 511 E8 分子背景

Laminin 511 E8 is a truncated laminin 511, which is one of the ECM proteins. laminin E8s serve as functionally minimal forms that retain the full capability for binding to integrins. Laminin 511-E8 consists of the C-terminal end of the alpha 5, beta 1, and gamma 1 chains. The laminin-511 heterotrimer (α5β1γ1) is one of the isoforms to be identified and a potent adhesive and pro-migratory substrate for a variety of normal and tumor cell lines in vitro. Previous studies indicated that laminin-511 contributes to tumor dissemination and metastasis in advanced breast carcinomas and other tumor types. Additionally, latest research uncovered that Laminin 511 might be a target antigen and involved in autoimmune pancreatitis.

Laminin 511 E8 前沿进展

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