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MAdCAM-1信息

英文名称:Mucosal addressin cell adhesion molecule-1
中文名称:黏膜地址素细胞黏附分子-1
靶点别称:Mucosal addressin cell adhesion molecule 1,MADCAM1,hMAdCAM-1,Mucosal Vascular Addressin Cell Adhesion Molecule 1,MACAM1,MAdCAM-1,Mucosal Addressin Cell Adhesion Molecule-1
上市药物数量:0
临床药物数量:1
最高研发阶段:批准上市

MAdCAM-1产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
MAM-H5253
Human
Human MAdCAM-1 Protein, Fc Tag (MALS verified)
 
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MAdCAM-1 分子别名

MAdCAM-1,Mucosal vascular addressin cell adhesion molecule 1 transcript variant 1

MAdCAM-1 分子背景

The mucosal addressin cell adhesion molecule-1 (MAdCAM-1) takes a key role in the endothelial adhesion and migration of lymphocytes to sites of inflammation in inflammatory disease. In vitro and in vivo data indicate that blockade of the adhesion molecule mucosal address in cell adhesion molecule (MAdCAM) pathway decreases leukocyte homing to the gut by inhibiting the interaction between MAdCAM and its ligand the α4β7 integrin expressed on lymphocytes.

MAdCAM-1 前沿进展

MAdCAM-1临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Ontamalimab SHP-647; PF-00547659; PF-547659 辉瑞 详情

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