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CLEC4C信息

英文名称:C-Type lectin domain family 4 member C
中文名称:C型凝集素结构域家族4成员C
靶点别称:DLEC,HECL,C-type lectin superfamily member 7,CLEC4C,BDCA2,UNQ9361/PRO34150,C-type lectin domain family 4 member C,Dendritic lectin,C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin, Superfamily Member 7,C-Type Lectin Domain Family 4, Member C,CLECSF11,CLECSF7,BDCA-2,C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin, Superfamily Member 11,Blood Dendritic Cell Antigen 2 Protein,Blood Dendritic Cell Antigen 2,Dendritic Cell Lectin B,CD303 Antigen,PRO34150,CD303
上市药物数量:0
临床药物数量:1
最高研发阶段:临床三期

CLEC4C产品列表

ACRO质量管理体系
 
评论(8)
CLC-H5245|Human CLEC4C / BDCA2 Protein, His Tag
  1. 139XXXXXXX2
  2. 0人赞
  3. 我们购买该产品用于SPR亲和力测定,该产品质量较好,包装也很好,还可回收。实验结果也比较符合我们的期待值,产品说明较为详细且方便。
  4. 2023-12-21
CLC-H5245|Human CLEC4C / BDCA2 Protein, His Tag
  1. 187XXXXXXX2
  2. 0人赞
  3. 我们使用产品来做抗原抗体的结合,主要应用在ELISA实验中,抗原包被使用量明显低于其他同类品牌,结合效率更高,使用方便。
  4. 2022-12-06
CLC-C52H4|Cynomolgus CLEC4C / BDCA2 Protein, His Tag (MALS verified)
  1. 159XXXXXXX6
  2. 0人赞
  3. 此蛋白主要用于检测抗体的结合活性,从ELISA实验的结果可以看出:能较好的拟合成一条“S”型曲线。蛋白稳定,复溶效果好。
  4. 2023-06-21
 

CLEC4C分子别名

DLEC,CLEC4C,BDCA-2,CD303,CLECSF11,CLECSF7, HECL

CLEC4C分子背景

CLEC4C (C-type lectin domain family 4 member C), also known as BDCA2, CLECSF11, CLECSF7, DLEC and CD303. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cell. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.

CLEC4C临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Litifilimab BIIB-059 临床三期 百健 皮肤红斑狼疮, 系统性红斑狼疮 详情

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