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TGF-beta 2信息

英文名称:Transforming growth factor beta 2
中文名称:转化生长因子β2
靶点别称:Prepro-Transforming Growth Factor Beta-2,Cetermin,Glioblastoma-Derived T-Cell Suppressor Factor,Polyergin,TGF-beta-2,BSC-1 Cell Growth Inhibitor,Transforming Growth Factor Beta 2,Transforming Growth Factor, Beta 2,TGFB2,LDS4,Transforming Growth Factor Bet
上市药物数量:0
临床药物数量:2
最高研发阶段:临床三期

TGF-beta 2产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
TG2-H4215
Human
Human TGF-Beta 2 / TGFB2 Protein, Tag Free
TG2-H8212
Human
Biotinylated Human TGF-Beta 2 / TGFB2 Protein, Avitag™
 
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TGF-beta 2 分子别名

TGFB2,MGC116892,TGFβ2,TGF-beta2

TGF-beta 2 分子背景

Transforming growth factor beta 2 ( TGFB2) is also known as TGF-β2, G-TSF, TGFB. is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The TGFB2 protein helps control the growth and division (proliferation) of cells, the process by which cells mature to carry out specific functions (differentiation), cell movement (motility), and the self-destruction of cells (apoptosis). The TGFB2 protein can inhibit the T cell growth by IL-2-dependent. and can inhibit immune surveillance during tumor development, the protein promoting tumor growth with an autocrine manner. TGF-β2 can affect the viability of killer cells and reduce the expression of IL-2, IL-6, IL-10, IFN-γ and other cytokines.TGFB2 plays an important role in controlling the immune system, and shows different activities on different types of cell, or cells at different developmental stages.

TGF-beta 2 前沿进展

TGF-beta 2临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
ENERGI-F701 ENERGI-F701 临床二期 Energenesis Biomedical 脱发 详情
Bintrafusp alfa M-7824; GSK-4045154; MSB-0011359C 临床三期 默克雪兰诺 胆管癌, 实体瘤, 三阴性乳腺肿瘤, 胆管上皮癌, 胆囊癌, 宫颈癌, 非小细胞肺癌 详情

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