GDF-8 分子别名
GDF-8, Myostatin, GDF8, MSTN, Growth/differentiation factor 8
GDF-8 分子背景
Growth differentiation factor 8 (GDF8), also known as myostatin, is a unique member of the transforming growth factor-β superfamily that is expressed in human granulosa cells and has important roles in regulating a variety of ovarian functions. GDF8 acts as a negative regulator of skeletal muscle growth and differentiation. In addition to the expression in the musculoskeletal system, GDF8 is also expressed in various tissues, including the reproductive system.
GDF-8 前沿进展