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IL-11信息

英文名称:Interleukin-11
中文名称:白介素11
靶点别称:Oprelvekin,IL-11,Interleukin 11,Adipogenesis inhibitory factor,AGIF
上市药物数量:1
临床药物数量:1
最高研发阶段:批准上市

IL-11产品列表

ACRO质量管理体系
 
评论(2)
IL1-H82E3|Biotinylated Human IL-11 Protein, His,Avitag™ (MALS verified)
  1. 185XXXXXXX0
  2. 4人赞
  3. 该产品用于药物发现高通量筛选,主要用于ELISA和FRET方法来进行高通量筛选,ACRO的IL-11与其受体具有很好的亲和力,使我们更加容易建立稳定的筛选体系。
  4. 2021-09-03
IL1-H5243|Human IL-11 Protein, His Tag, premium grade
  1. 134XXXXXXX0
  2. 1人赞
  3. 该产品主要用来噬菌体淘选实验中的淘选IL-11靶点,该蛋白携带生物素标签,在二轮液相淘选中富集了1700倍,后续可用于进一步的验证。
  4. 2023-01-17
 

IL-11分子别名

IL-11,Interleukin-11,AGIF,Oprelvekin,IL11

IL-11分子背景

Interleukin-11 (IL-11) is a pleiotropic cytokine that stimulates megakaryocytopoiesis, resulting in increased production of platelets, as well as activating osteoclasts, inhibiting epithelial cell proliferation and apoptosis, and inhibiting macrophage mediator production. These functions may be particularly important in mediating the hematopoietic, osseous and mucosal protective effects of IL-11. The cytokine also possesses anti-inflammatory activity, and has been proposed as a therapeutic agent in the treatment of chronic inflammatory diseases, such as Crohn's disease and rheumatoid arthritis. Although IL-11 was initially believed to be restricted to mammals, subsequent studies demonstrated it to be expressed in fish. Despite close similarity in gene structure and conservation of key amino acids between fish and mammalian IL-11, they share relatively low overall amino acid identity and may not necessarily be functionally analogous.

IL-11上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验
Recombinant human interleukin-11 (Hangzhou Jiuyuan Gene Engineering Co Ltd ) 重组人白细胞介素-11(杭州九源基因工程有限公司) 批准上市 杭州九源基因工程有限公司 血小板减少 详情

IL-11临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
9MW3811 9MW3811 临床一期 迈威(上海)生物科技股份有限公司 实体瘤, 特发性肺纤维化, 肿瘤, 纤维化, 肺纤维化 详情
LASN-03 Lassen Therapeutics 详情

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