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IL-11信息

英文名称:Interleukin-11
中文名称:白介素11
靶点别称:Oprelvekin,IL-11,Interleukin 11,Adipogenesis inhibitory factor,AGIF
上市药物数量:0
临床药物数量:0
最高研发阶段:批准上市

IL-11产品列表

 
评论(1)
IL1-H82E3|Biotinylated Human IL-11 Protein, His,Avitag™ (MALS verified)
  1. 185XXXXXXX0
  2. 0人赞
  3. 该产品用于药物发现高通量筛选,主要用于ELISA和FRET方法来进行高通量筛选,ACRO的IL-11与其受体具有很好的亲和力,使我们更加容易建立稳定的筛选体系。
  4. 2021-09-03
 

IL-11 分子别名

IL-11,Interleukin-11,AGIF,Oprelvekin,IL11

IL-11 分子背景

Interleukin-11 (IL-11) is a pleiotropic cytokine that stimulates megakaryocytopoiesis, resulting in increased production of platelets, as well as activating osteoclasts, inhibiting epithelial cell proliferation and apoptosis, and inhibiting macrophage mediator production. These functions may be particularly important in mediating the hematopoietic, osseous and mucosal protective effects of IL-11. The cytokine also possesses anti-inflammatory activity, and has been proposed as a therapeutic agent in the treatment of chronic inflammatory diseases, such as Crohn's disease and rheumatoid arthritis. Although IL-11 was initially believed to be restricted to mammals, subsequent studies demonstrated it to be expressed in fish. Despite close similarity in gene structure and conservation of key amino acids between fish and mammalian IL-11, they share relatively low overall amino acid identity and may not necessarily be functionally analogous.

IL-11 前沿进展

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