IL-11 靶点蛋白|抗体药物|临床药物信息

IL-11信息

英文名称：Interleukin-11
中文名称：白介素11
靶点别称：Oprelvekin，IL-11，Interleukin 11，Adipogenesis inhibitory factor，AGIF

上市药物数量：1
临床药物数量：0
最高研发阶段：批准上市

IL-11产品列表

筛选结果

产品库

在线 (5)

物种

标签

属性

Protein (5)

标记

货号	物种	产品描述
IL1-H5243	Human	ActiveMax® Human IL-11 Protein, His Tag
IL1-H82E3	Human	Biotinylated Human IL-11 Protein, His,Avitag™ (MALS verified)
IL1-H5269	Human	Human IL-11 Protein, Fc Tag (MALS verified)
IL1-C5243	Cynomolgus	Cynomolgus IL-11 Protein, His Tag
IL1-M5243	Mouse	Mouse IL-11 Protein, Fc Tag

IL1-H82E3|Biotinylated Human IL-11 Protein, His,Avitag™ (MALS verified)

185XXXXXXX0

2人赞

该产品用于药物发现高通量筛选，主要用于ELISA和FRET方法来进行高通量筛选，ACRO的IL-11与其受体具有很好的亲和力，使我们更加容易建立稳定的筛选体系。
2021-09-03

IL1-H5243|ActiveMax® Human IL-11 Protein, His Tag

134XXXXXXX0

1人赞

该产品主要用来噬菌体淘选实验中的淘选IL-11靶点，该蛋白携带生物素标签，在二轮液相淘选中富集了1700倍，后续可用于进一步的验证。
2023-01-17

IL-11 分子别名

IL-11,Interleukin-11,AGIF,Oprelvekin,IL11

IL-11 分子背景

Interleukin-11 (IL-11) is a pleiotropic cytokine that stimulates megakaryocytopoiesis, resulting in increased production of platelets, as well as activating osteoclasts, inhibiting epithelial cell proliferation and apoptosis, and inhibiting macrophage mediator production. These functions may be particularly important in mediating the hematopoietic, osseous and mucosal protective effects of IL-11. The cytokine also possesses anti-inflammatory activity, and has been proposed as a therapeutic agent in the treatment of chronic inflammatory diseases, such as Crohn's disease and rheumatoid arthritis. Although IL-11 was initially believed to be restricted to mammals, subsequent studies demonstrated it to be expressed in fish. Despite close similarity in gene structure and conservation of key amino acids between fish and mammalian IL-11, they share relatively low overall amino acid identity and may not necessarily be functionally analogous.

IL-11 前沿进展

IL-11上市药物信息

英文名称	中文名称	研发代码	研发阶段	公司	最早商品名	最早批准国家	最早适应症	最早批准公司	最早批准日期	适应症	临床试验
Recombinant human interleukin-11 (Hangzhou Jiuyuan Gene Engineering Co Ltd )	重组人白细胞介素-11（杭州九源基因工程有限公司）		批准上市	杭州九源基因工程有限公司						血小板减少	详情

会议日历

会议一览

IL-11