搜索
 > 【MARCO】

MARCO产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
MAR-C5248
Cynomolgus
Cynomolgus MARCO Protein, His Tag
MAR-M5245
Mouse
Mouse MARCO Protein, His Tag
MAR-H82E4
Human
Biotinylated Human MARCO Protein, Avitag™,His Tag
MAR-H5243
Human
Human MARCO Protein, His Tag
MAR-M5246
Mouse
Mouse MARCO (421-518) Protein, His Tag
 
评论(0)
 

MARCO 分子别名

MARCO, SCARA2, Macrophage receptor with collagenous structure, Scavenger receptor class A member 2

MARCO 分子背景

MARCO is also known as Scavenger receptor class A member 2 and SCARA2. Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria. Also plays a role in binding of unopsonized particles by alveolar macrophages. Binds to the secretoglobin SCGB3A2. MARCO ligation promotes the production of inflammatory mediators by macrophages. MARCO mediated internalization of some ligands prevents their activation of cell surface TLR4 but enables their activation of intracellular TLR3. MARCO contributes to the clearance of apoptotic cells and inhaled bacteria, mast cell mediated silicosis, and the amelioration of allergen or ozone induced lung inflammation. It is required for the organization of the splenic marginal zone and the interaction of splenic macrophages and B cells.

MARCO 前沿进展

消息提示

请输入您的联系方式,再点击提交!

确定