CD45 靶点蛋白|抗体药物|临床药物信息

CD45信息

英文名称：Leukocyte common antigen
中文名称：白细胞共同抗原
靶点别称：PTPRC，T200，CD45，Protein Tyrosine Phosphatase， Receptor Type C，CD45 Antigen，L-CA，Protein Tyrosine Phosphatase， Receptor Type， C Polypeptide，Receptor-Type Tyrosine-Protein Phosphatase C，T200 Leukocyte Common Antigen，Leukocyte Common Antigen，T200 Glycoprotein，EC 3.1.3.48，CD45R，GP180，B220，LCA，LY5，Leukocyte Common Antigens，Protein Tyrosine Phosphatase Receptor Type C，EC:3.1.3.48

上市药物数量：0
临床药物数量：3
最高研发阶段：临床三期

CD45产品列表

筛选结果

产品库

在线 (4)

物种

Human (4)

标签

属性

Protein (4)

标记

货号	物种	产品描述
CD5-H52H8	Human	Human CD45 / PTPRC protein, His Tag
CD5-H82E7	Human	Biotinylated Human CD45 / PTPRC protein, His,Avitag™ (MALS verified)
CD5-H52H9	Human	Human CD45 / PTPRC (26-482) protein, His Tag
CD5-H5259	Human	Human CD45 / PTPRC Protein, Llama IgG2b Fc Tag, low endotoxin

CD5-H82E7|Biotinylated Human CD45 / PTPRC protein, His,Avitag™ (MALS verified)

+49XXXXXXX4732

2人赞

Dear Sir or Madam, I had an overall good service from Acro Biosystems. Shipment was fast and product quality was good. Got the protocol for QC after asking the customer service. Protocol for QC was easy to understand and repeat. Easy way to download the Certificate of Analysis via the printed QR code on product vials. Customer service answered very fast and was very friendly. QC of biotinylated human CD45 protein vs. Human Galectin-1 protein (GA1-H4113) was fine. Biotinylated human CD45 protein worked fine and could be loaded on Streptavidin biosensors (Octet system).
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2022-01-01

CD5-H5259|Human CD45 / PTPRC Protein, Llama IgG2b Fc Tag, low endotoxin

130XXXXXXX2

0人赞

Human CD155蛋白与TIGIT蛋白的结合是现在靶向药物研究的热点，该产品用于靶向TIGIT抗体的竞争ELISA方法开发中重复性好，分装保存性质稳定，重现性好，质量比较可靠！
2023-01-31

CD45 分子别名

CD45,PTPRC,L-CA,T200

CD45 分子背景

CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.

CD45 前沿进展

CD45临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
Immunomodulatory progenitor cell therapy (Celixir)		临床三期	Celixir	心内膜心肌纤维化, 心肌疾病	详情
At 211 MAb BC8-B10		临床二期	弗莱德哈钦森癌症研究中心	肿瘤	详情
I-131-Apamistamab	BC8-I-131; BC-8	临床三期	弗莱德哈钦森癌症研究中心	间变大细胞淋巴瘤, 全血细胞减少, Sezary综合征, Burkitt淋巴瘤, 眼内淋巴瘤, 非霍奇金淋巴瘤, 淋巴瘤, 急性髓细胞样白血病, T-细胞淋巴瘤, 滤泡中心淋巴瘤, 皮肤T细胞淋巴瘤, 华氏巨球蛋白血症, 铁粒幼细胞性贫血, 性腺组织肿瘤, 慢性淋巴细胞白血病, T-细胞白血病, 大颗粒淋巴细胞白血病, 蕈样真菌病, 霍奇金病, 边缘带B细胞淋巴瘤, 白血病, 周围T-细胞淋巴瘤, 循环肿瘤细胞, 造血干细胞移植, 毛细胞白血病, 难治性贫血伴原始细胞过多, 弥漫性大B-细胞淋巴瘤, B-细胞淋巴瘤, 慢性骨髓单核细胞性白血病, 骨髓增生异常综合征, 淋巴瘤样肉芽肿病, 淋巴瘤，大细胞，免疫母细胞, 前体B-细胞成淋巴细胞白血病-淋巴瘤, 急性淋巴细胞白血病, 套细胞淋巴瘤	详情

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CD45