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> 【CD45】
CD45信息
英文名称：Leukocyte common antigen
中文名称：白细胞共同抗原
靶点别称：PTPRC，T200，CD45，Protein Tyrosine Phosphatase， Receptor Type C，CD45 Antigen，L-CA，Protein Tyrosine Phosphatase， Receptor Type， C Polypeptide，Receptor-Type Tyrosine-Protein Phosphatase C，T200 Leukocyte Common Antigen，Leukocyte Common Antigen，T200 Glycoprotein，EC 3.1.3.48，CD45R，GP180，B220，LCA，LY5，Leukocyte Common Antigens，Protein Tyrosine Phosphatase Receptor Type C，EC:3.1.3.48
中文名称：白细胞共同抗原
靶点别称：PTPRC，T200，CD45，Protein Tyrosine Phosphatase， Receptor Type C，CD45 Antigen，L-CA，Protein Tyrosine Phosphatase， Receptor Type， C Polypeptide，Receptor-Type Tyrosine-Protein Phosphatase C，T200 Leukocyte Common Antigen，Leukocyte Common Antigen，T200 Glycoprotein，EC 3.1.3.48，CD45R，GP180，B220，LCA，LY5，Leukocyte Common Antigens，Protein Tyrosine Phosphatase Receptor Type C，EC:3.1.3.48
上市药物数量：0
临床药物数量：3
最高研发阶段：临床三期
临床药物数量：3
最高研发阶段：临床三期
CD45产品列表
产品库
物种
属性
| 货号 | 物种 | 产品描述 | 蛋白结构 | 纯度 | 活性 |
|---|---|---|---|---|---|
| CD5-H52H8 |
 Human |
Human CD45 / PTPRC protein, His Tag |
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| CD5-H82E7 |
Human |
Biotinylated Human CD45 / PTPRC protein, His,Avitag™ (MALS verified) |
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| CD5-H52H9 |
Human |
Human CD45 / PTPRC (26-482) protein, His Tag |
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CD45 分子别名
CD45,PTPRC,L-CA,T200
CD45 分子背景
CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.
