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货号 物种 产品描述 蛋白结构 纯度 活性
ZN3-H52H3
Human
Human ZNRF3 protein, His Tag (MALS verified)
 
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ZNRF3 分子别名

ZNRF3, Zinc/RING finger protein 3, RING-type E3 ubiquitin transferase ZNRF3, RING finger protein 203, KIAA1133, RNF203

ZNRF3 分子背景

The transmembrane E3 ubiquitin ligase zinc and ring finger 3 (ZNRF3) is a negative feedback regulator of Wnt signalling. ZNRF3 is associated with the Wnt receptor complex, and inhibits Wnt signalling by promoting the turnover of frizzled and LRP6 and acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway.

ZNRF3 前沿进展

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