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KREMEN1产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
KR1-H5253
Human
Human Kremen-1 protein, Fc Tag
ACRO质量管理体系
 
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KREMEN1 分子别名

KREMEN, KRM1,Dickkopf receptor/Kringle domain-containing transmembrane protein 1/Kringle-containing protein marking the eye and the nose

KREMEN1 分子背景

Kremens are high-affinity receptors for Dickkopf 1 (Dkk1) and regulate the Wnt/β-catenin signaling pathway by down-regulating the low-density lipoprotein receptor-related protein 6 (LRP6). Kremen1 is considered as one component of a membrane complex modulating canonical Wnt signalling through LRP6 in vertebrates. Additionally, KREMEN1 (KRM1) has also been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD).

KREMEN1 前沿进展

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