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ASGR1信息

英文名称:Asialoglycoprotein receptor 1
中文名称:去唾液酸糖蛋白受体-1
靶点别称:C-type lectin domain family 4 member H1,HL-1,Hepatic lectin H1,ASGPR 1,ASGR1,Asialoglycoprotein Receptor 1,CLEC4H1,ASGP-R 1,ASGPR1,ASGPR
上市药物数量:0
临床药物数量:1
最高研发阶段:临床前

ASGR1 分子别名

ASGP-R 1, ASGPR 1, C-type lectin domain family 4 member H1, Hepatic lectin H1, HL-1

ASGR1 分子背景

ASGPR, a transmembrane C-type lectin, recognizes a wide variety of ligands that contain either terminal galactose (Gal) or N-acetylgalactosamine (GalNAc) residues and has been identified as a highly selective receptor on hepatocytes. The ASGR is composed of both a major (ASGR1) and minor subunit (ASGR2). ASGR1 has been shown to be efficiently targeted to the plasma membrane and to undergo constitutive endocytosis and recycling and found mainly expressed in the human liver.

ASGR1 前沿进展

ASGR1临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
AMG-529 AMG529; AMG-529 安进 详情

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