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> 【ASGR1】
ASGR1信息
英文名称：Asialoglycoprotein receptor 1
中文名称：去唾液酸糖蛋白受体-1
靶点别称：C-type lectin domain family 4 member H1，HL-1，Hepatic lectin H1，ASGPR 1，ASGR1，Asialoglycoprotein Receptor 1，CLEC4H1，ASGP-R 1，ASGPR1，ASGPR
中文名称：去唾液酸糖蛋白受体-1
靶点别称：C-type lectin domain family 4 member H1，HL-1，Hepatic lectin H1，ASGPR 1，ASGR1，Asialoglycoprotein Receptor 1，CLEC4H1，ASGP-R 1，ASGPR1，ASGPR
上市药物数量：0
临床药物数量：1
最高研发阶段：临床前
临床药物数量：1
最高研发阶段：临床前
ASGR1产品列表
产品库
物种
属性
| 货号 | 物种 | 产品描述 | 蛋白结构 | 纯度 | 活性 |
|---|---|---|---|---|---|
| AS1-H5253 |
 Human |
Human ASGR1 / ASGPR1 Protein, Fc Tag (MALS verified) |
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  |
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| GS1-H82Q3 |
Human |
Biotinylated Human ASGR1 / ASGPR1, His,Avitag™ |
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ASGR1 分子别名
ASGP-R 1, ASGPR 1, C-type lectin domain family 4 member H1, Hepatic lectin H1, HL-1
ASGR1 分子背景
ASGPR, a transmembrane C-type lectin, recognizes a wide variety of ligands that contain either terminal galactose (Gal) or N-acetylgalactosamine (GalNAc) residues and has been identified as a highly selective receptor on hepatocytes. The ASGR is composed of both a major (ASGR1) and minor subunit (ASGR2). ASGR1 has been shown to be efficiently targeted to the plasma membrane and to undergo constitutive endocytosis and recycling and found mainly expressed in the human liver.
ASGR1 前沿进展
ASGR1临床药物信息
| 英文名称 | 研发代码 | 研发阶段 | 公司 | 适应症 | 临床试验 |
|---|---|---|---|---|---|
| AMG-529 | AMG529; AMG-529 | 安进 | 详情 |
