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Siglec-7信息

英文名称:Sialic acid-binding Ig-like lectin 7
中文名称:唾液酸结合免疫球蛋白样凝集素-7
靶点别称:CDw328,AIRM-1,Adhesion inhibitory receptor molecule 1,D-siglec,QA79 membrane protein,CD328
上市药物数量:0
临床药物数量:0
最高研发阶段

Siglec-7 分子别名

CDw328, D-siglec, A79 membrane protein, p75,Adhesion inhibitory receptor molecule 1, AIRM-1

Siglec-7 分子背景

Siglec-7 is a member of the human CD33‐related Siglec receptor. The extracellular region of Siglec‐7 is characterized by an N‐terminal V‐set Ig domain that can bind sialic acid and two C2‐set Ig domains. The cytoplasmic tail of Siglec‐7 has one immune‐receptor tyrosine‐based inhibitory motif (ITIM) and one ITIM‐like motif. Siglec-7 is considered as a sialic acid-dependent immunoreceptor with inhibitory potential and expressed predominantly on human NK cells, monocytes and a small subset of CD8+ T cells.

Siglec-7 前沿进展

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