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Frizzled-10信息

英文名称:Frizzled-10
中文名称:卷曲蛋白受体10
靶点别称:Frizzled Class Receptor 10,FZD10,Frizzled 10, Seven Transmembrane Spanning Receptor,Frizzled Family Receptor 10,HFz10,FzE7,Frizzled (Drosophila) Homolog 10,Frizzled Homolog 10 (Drosophila),Frizzled Homolog 10,CD350 Antigen,Frizzled-10,CD350,Fz-10,Fz10
上市药物数量:0
临床药物数量:1
最高研发阶段:终止

Frizzled-10产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
FRD-H52H3
Human
Human Frizzled-10 / FZD10 Protein, His Tag (MALS verified)
 
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Frizzled-10 分子别名

Fz-10, FZD10, hFz10, FzE7, CD350

Frizzled-10 分子背景

Frizzled-10 (FZD10) is also known as FzE7 or CD350, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD10 contains one FZ (frizzled) domain. FZD10 protein is a cell surface receptor, which is activated by Wnt proteins and involved in the regulation of cellular function. FZD10 interacts with WNT7B and MYOC.

Frizzled-10 前沿进展

Frizzled-10临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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