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Netrin-1信息

英文名称:Netrin 1
中文名称:神经轴突导向因子1
靶点别称:Netrin-1,Netrin 1, Mouse, Homolog Of,MRMV4,Epididymis tissue protein Li 131P,NTN1L
上市药物数量:0
临床药物数量:1
最高研发阶段:临床二期

Netrin-1产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
NE1-H52H3
Human
Human Netrin-1 Protein, His Tag
 
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Netrin-1 分子别名

Netrin-1,NTN1,NTN1L,Netrin1,netrin 1

Netrin-1 分子背景

Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion. Involved in dorsal root ganglion axon projection towards the spinal cord. It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.

Netrin-1 前沿进展

Netrin-1临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
NP-137 NP-137 Netris Pharma, Centre Leon Berard 详情

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