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MUC-17信息

英文名称:Mucin-17
中文名称:黏蛋白-17
靶点别称:Small intestinal mucin-3,MUC-3
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

MUC-17产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
MU7-H52H3
Human
Human MUC-17 Protein, His Tag
 
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MUC-17 分子别名

Mucin-17,MUC-17,MUC17,MUC-3,MUC3

MUC-17 分子背景

Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.

MUC-17 前沿进展

MUC-17临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
AMG-199 AMG-199 临床一期 安进 实体瘤, 胃癌, 食道癌 详情

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