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NRG1 Beta 1产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
NR1-H5268
Human
Human NRG1 Beta 1 Protein, Fc Tag
 
评论(1)
NR1-H5268|Human NRG1 Beta 1 Protein, Fc Tag
  1. 136XXXXXXX7
  2. 1人赞
  3. 使用这个蛋白进行抗体筛选,获得的抗体效价和亲和力都符合要求,然后使用这个蛋白与配体蛋白反应,反应性明显比别公司的同样蛋白要强很多,同时由于这个蛋白标记Fc标签,对后续操作方便了很多。总之很满意。
  4. 2022-03-24
 

NRG1 Beta 1 分子别名

NRG1 Beta 1,HRG1 beta 1,Neuregulin-1 beta 1,Neuregulin1 beta 1,NRG1,ARIA,GGF,HGL,HRGA,NDF,SMDF

NRG1 Beta 1 分子背景

NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specific and differ significantly in their structure. The HRG isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like domains; and the SMDF isoform shares only the EGF-like domain with other isoforms. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through their displayed interaction with ERBB receptors, NRG1 isoforms induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells.

NRG1 Beta 1 前沿进展

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