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CD59信息

英文名称:CD59 glycoprotein
中文名称:CD59糖蛋白
靶点别称:CD59 Antigens,Membrane attack complex inhibition factor,Membrane inhibitor of reactive lysis,MEM43 antigen,HRF-20,MIRL,20 kDa homologous restriction factor,MAC-inhibitory protein,MACIF,Protectin,MAC-IP,1F5 antigen,P18-20,CD59 Molecule, Complement Regulatory Protein,MSK21,CD59 Antigen, Complement Regulatory Protein,16.3A5,Lymphocytic Antigen CD59/MEM43,MIC11,MIN1,Ly-6-Like Protein,1F5,T Cell-Activating Protein,CD59 Antigen,EJ30,MIN2,MIN3,EL32,Surface Anitgen Recognized By Monoclonal Antibody 16.3
上市药物数量:0
临床药物数量:1
最高研发阶段:临床前

CD59产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
CD9-H52H9
Human
Human CD59 Protein, His Tag
CD9-H82E3
Human
Biotinylated Human CD59 Protein, His,Avitag™
 
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CD59 分子别名

CD59,16.3A5,1F5,EJ16,EJ30,EL32,FLJ38134,FLJ92039,G344,HRF20,MAC-IP,MACIF,MEM43,MGC2354,MIC11,MIN1,MIN2,MIN3,MIRL,MSK21,p18-20,Protectin

CD59 分子背景

CD59, also known as membrane attack complex inhibition factor (MACIF), Protectin, 1F5 antigen, HRF-20 and MIRL. CD59 has been identified as a glycosylphosphatidylinositol-anchored membrane protein that acts as an inhibitor of the formation of the membrane attack complex to regulate complement activation. Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.

CD59 前沿进展

CD59临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
HMR-59 HMR-59 塔夫茨大学 详情

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