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CD6信息

英文名称:T-cell differentiation antigen CD6
中文名称:T细胞分化抗原CD6
靶点别称:T12,CD6,CD6 Molecule,TP120,T-Cell Differentiation Antigen CD6,CD6 Antigen
上市药物数量:1
临床药物数量:0
最高研发阶段:批准上市

CD6产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
CD6-H52H7
Human
Human CD6 / TP120 Protein, His Tag
 
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CD6 分子别名

CD6,TP120,T12

CD6 分子背景

CD6 (Cluster of Differentiation 6) is a cell surface glycoprotein that is involved in T cell activation and a member of the scavenger receptor cysteine rich protein superfamily (SRCRSF). CD6 is expressed at low levels on immature thymocytes and at high levels on mature thymocytes. The majority of peripheral blood T cells, a subset of B cells, and a subset of neuronal cells express CD6. CD6 appears to play a role as both a costimulatory molecule in T cell activation and as an adhesion receptor. Studies demonstrating a mitogenic effect for T cells with some CD6 specific monoclonal antibodies, in conjunction with either accessory cells or PMA and anti-CD2 mAb, support the concept of CD6 as a co stimulatory molecule.

CD6 前沿进展

CD6上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验
Itolizumab Bmab-600; T-1-h; EQ-001; T-1-hT; h-T1 批准上市 Biocon, Center Of Molecular Immunology, 百泰生物药业有限公司 Alzumab India 斑块银屑病 Biocon 2013-01-01 移植物抗宿主病, 皮肤红斑狼疮, 狼疮肾炎, 冠状病毒感染, 银屑病, 哮喘, 斑块银屑病 详情

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