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GAS6信息

英文名称:Growth arrest-specific protein 6
中文名称:生长停滞特异性蛋白6
靶点别称:GAS6,AXLLG,Growth Arrest Specific 6,AXL Receptor Tyrosine Kinase Ligand,AXL Stimulatory Factor,Growth Arrest-Specific Protein 6,GAS-6,AXSF,FLJ34709,DKFZp666G247
上市药物数量:0
临床药物数量:1
最高研发阶段:临床三期

GAS6产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
GA6-H5249
Human
Human GAS6 (279-678) Protein, His Tag (MALS verified)
 
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GAS6 分子别名

GAS6,GAS-6,AXLLG

GAS6 分子背景

GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG. Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

GAS6 前沿进展

GAS6临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Batiraxcept AVB-500; Aravive S-6; AVB-S6-500; Ruga-S6; 3D-229; 3D229 临床三期 Aravive Inc 卵巢癌, 实体瘤, 肾细胞癌, 免疫球蛋白a肾病, 卵巢上皮癌, 肿瘤, 尿路上皮癌, 胰腺癌, 腹膜癌, 输卵管癌 详情

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