GAS6 靶点蛋白|抗体药物|临床药物信息

GAS6信息

英文名称：Growth arrest-specific protein 6
中文名称：生长停滞特异性蛋白6
靶点别称：GAS6，AXLLG，Growth Arrest Specific 6，AXL Receptor Tyrosine Kinase Ligand，AXL Stimulatory Factor，Growth Arrest-Specific Protein 6，GAS-6，AXSF，FLJ34709，DKFZp666G247

上市药物数量：0
临床药物数量：1
最高研发阶段：临床三期

GAS6产品列表

筛选结果

产品库

在线 (1)

物种

Human (1)

标签

His Tag (1)

属性

Protein (1)

标记

Unconjugated (1)

货号	物种	产品描述	蛋白结构	纯度	活性
GA6-H5249	Human	Human GAS6 (279-678) Protein, His Tag (MALS verified)

GAS6 分子别名

GAS6,GAS-6,AXLLG

GAS6 分子背景

GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG. Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

GAS6 前沿进展

GAS6临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
Batiraxcept	AVB-500; Aravive S-6; AVB-S6-500; Ruga-S6; 3D-229; 3D229	临床三期	Aravive Inc	卵巢癌, 实体瘤, 肾细胞癌, 免疫球蛋白a肾病, 卵巢上皮癌, 肿瘤, 尿路上皮癌, 胰腺癌, 腹膜癌, 输卵管癌	详情

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GAS6