CLEC12A 靶点蛋白|抗体药物|临床药物信息

CLEC12A信息

英文名称：C-Type lectin domain family 12 member A
中文名称：C型凝集素结构域家族12成员A
靶点别称：CD371 Antigen，C-Type Lectin-Like Molecule 1，MICL，CD371，CLEC12A，DCAL2，DCAL-2，Dendritic cell-associated lectin 2，C-Type Lectin Domain Family 12 Member A，Myeloid Inhibitory C-Type Lectin-Like Receptor，CLL-1，CLL1，C-Type Lectin Domain Family 12， Member A，C-Type Lectin-Like Molecule-1，C-Type Lectin Protein CLL-1

上市药物数量：0
临床药物数量：15
最高研发阶段：临床三期

CLEC12A产品列表

筛选结果

产品库

在线 (10)

物种

标签

属性

Protein (10)

标记

货号	物种	产品描述
CLA-H5266	Human	Human CLEC12A / MICL / CLL-1 Protein, Fc Tag (MALS verified)
CLA-H5245	Human	Human CLEC12A / MICL / CLL-1 Protein, His Tag
CLA-HF247	Human	FITC-Labeled Human CLEC12A / MICL / CLL-1 Protein, His Tag
CLA-H82E6	Human	Biotinylated Human CLEC12A / MICL / CLL-1 Protein, His,Avitag™
CLA-H82F7	Human	Biotinylated Human CLEC12A / MICL / CLL-1 Protein, Fc,Avitag™
CLA-M5244	Mouse	Mouse CLEC12A / MICL / CLL-1 Protein, His Tag
CLA-R5248	Rat	Rat CLEC12A / MICL / CLL-1 Protein, His Tag
CLA-HP2Q3	Human	PE-Labeled Human CLEC12A / MICL / CLL-1 Protein, His Tag (Site-specific conjugation)
CLA-C5246	Cynomolgus	Cynomolgus CLEC12A / MICL / CLL-1 Protein, His Tag
CLA-HA248	Human	APC-Labeled Human CLEC12A / MICL / CLL-1 Protein, His Tag (Site-specific conjugation)

CLA-HF247|FITC-Labeled Human CLEC12A / MICL / CLL-1 Protein, His Tag

130XXXXXXX1

0人赞

性价比超高，用于流式检测效果非常好，检测结果清晰可判重复性较好而且结果稳定产品储存的时间也足够长，使用感很好
>
2023-02-23

CLA-H82E6|Biotinylated Human CLEC12A / MICL / CLL-1 Protein, His,Avitag™

180XXXXXXX9

0人赞

biotin-CLL-1，主要用于噬菌体液相筛选，ELISA检测该抗原蛋白与阳参的结合活性正常，已经顺利用于抗体的筛选
>
2022-12-17

CLA-H5245|Human CLEC12A / MICL / CLL-1 Protein, His Tag

136XXXXXXX0

0人赞

购买该蛋白用于小鼠免疫，该蛋白纯度高，免疫原性强，多次购买，经过实验验证，使用该蛋白对小鼠进行免疫，可以达到较高的滴度，所以多次购买该产品。
>
2022-09-15

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CLEC12A 分子别名

CLEC12A,MICL,CLL-1,CLL1,DCAL2,DCAL-2,CD371

CLEC12A 分子背景

CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.

CLEC12A 前沿进展

CLEC12A临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
CLL1+CD33 CAR-T(Zhejiang University)		临床一期	浙江大学	急性髓细胞样白血病	详情
CLL1-CD33 cCART cell therapy (iCell Gene Therapeutics)	CLL1-CD33-cCAR	临床一期	归气丹生物医药（香港）有限公司, 成都军区总医院	慢性髓细胞白血病, 血液肿瘤, 骨髓增生异常综合征, 骨髓增生性疾病, 急性髓细胞样白血病	详情
KITE-222		临床一期	Kite Pharma	急性髓细胞样白血病	详情
Anti-CD33/CLL1 CAR-NK Cell Therapy		临床一期	英百瑞（杭州）生物医药有限公司	急性髓细胞样白血病	详情
CLL1 CAR-T(Zhejiang University)		临床一期	浙江大学	急性髓细胞样白血病	详情
CLL1 CAR T-cell Therapy(Yake Biotechnology)		临床一期	上海雅科生物科技有限公司	急性髓细胞样白血病	详情
ICG-136	ICG-136; 123b-33bcCAR	临床一期	归气丹生物医药（香港）有限公司	急性髓细胞样白血病	详情
Anti-CLL1 CAR T cell therapy(Soochow University)		临床二期	苏州大学附属第一医院	急性髓细胞样白血病	详情
CD123/CLL1 CAR-T Cell Therapy (Fujian Medical University)		临床三期	福建医科大学	急性髓细胞样白血病	详情
Anti-CD33/CLL-1 CAR-T (Legend)		临床一期	Legend Biotech Corp	急性早幼粒细胞白血病	详情
CLL-1.CAR T cell therapy (Baylor College of Medicine)		临床一期	贝勒医学院	急性髓细胞样白血病	详情
Anti-CLL1 CAR-T (Guangzhou Bio-Gene)	BG-1805; BG1805	临床一期	广州百暨基因科技有限公司	急性髓细胞样白血病	详情
CLL-1/CD33 Targeted LCAR-AMDR Cells（Nanjing Legend Biotechnology）		临床一期	南京传奇生物科技有限公司	急性髓细胞样白血病	详情
Tepoditamab	MCLA-117	临床一期	Pharmaceutical Research Associates, Institute Gustave-Roussy, Merus Nv, Vu University Medical Center, Lgc	急性髓细胞样白血病	详情

会议日历

会议一览

CLEC12A