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VEGF165

VEGF165信息

英文名称:Vascular endothelial growth factor A上市药物数量50
中文名称血管内皮生长因子A临床药物数量60
靶点别称Vascular Endothelial Growth Factor，VEGF-A，MVCD1，Vascular endothelial growth factor A，VEGF，VEGFA，VPF，Vascular Endothelial Growth Factor A165，Vascular permeability factor，Vascular Endothelial Growth Factor A121最高研发阶段批准上市
英文名称:Vascular endothelial growth factor A
中文名称血管内皮生长因子A
靶点别称Vascular Endothelial Growth Factor，VEGF-A，MVCD1，Vascular endothelial growth factor A，VEGF，VEGFA，VPF，Vascular Endothelial Growth Factor A165，Vascular permeability factor，Vascular Endothelial Growth Factor A121
上市药物数量50
临床药物数量60
最高研发阶段Approved

VEGF165产品列表

  • 属性

    Protein (7)Beads (1)Kits (1)

  • 产品库

    在线 (9)

  • 物种

    Human (9)

  • 标签

    Tag Free (4)His Tag (2)His Tag & Avi Tag (1)- (2)

  • 标记

    Unconjugated (4)Biotin-labeled (2)FITC Labeled (1)- (2)

共 9 项数据
  • 1

VEGF165分子背景

VEGF165 is the most abundant splice variant of VEGF-A. VEGF165 is produced by a number of cells including endothelial cells, macrophages and T cells. VEGF165 is involved in angiogenesis, vascular endothelial cell survival, growth, migration and vascular permeability. VEGF gene expression is induced by hypoxia, inflammatory cytokines and oncogenes. VEGF165 binds to heparan sulfate and is retained on the cell surface and in the extracellular matrix. VEGF165 binds to the receptor tyrosine kinases, VEGFR1 and VEGFR2. VEGF165 is the only splice variant that binds to co-receptors NRP-1 and NRP-2 that function to enhance VEGFR2 signaling. Binding of VEGF165 to VEGFR1 and VEGFR2 leads to activation of the PI3K/AKT, p38 MAPK, FAK and paxillin. VEGF plays a key role in tumor angiogenesis in many cancers.

VEGF165分子别名

RP1-261G23.1,MGC70609,MVCD1,VEGFA,VPF

产品评论

  • qi***********harbourbiomed.com 2026-01-29
    0人点赞
    Biotinylated Human VEGF165 Protein, His,Avitag™ (HPLC verified)
    买了很多次蛋白，各种包装的用于酶联免疫吸附试验，蛋白质量很好，发货速度也很快
  • 13*********126.com 2026-01-13
    0人点赞
    Human VEGF165 Protein, His Tag, low endotoxin (MALS verified)
    之前选购了没有 tag 的 VEGF165 活性很好，现在项目需求要做 spr，买了 his tag 的 VEGF165，已经 ELISA 检测了活性，期待 spr 的结果。
  • ga*******126.com 2025-12-19
    0人点赞
    Human VEGF165 Protein, His Tag, low endotoxin (MALS verified)
    买该蛋白主要用于噬菌体展示抗体库的筛选与验证实验。其高活性高纯度，大大增加了筛选成功率，高特异性极大地保证了实验背景的干净，使得结果高度稳定且可重复，为我们的数据质量提供了坚实保障。供应商的物流响应迅速，服务态度也非常贴心，强烈推荐同行试用。
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