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VEGF165

VEGF165信息

英文名称:Vascular endothelial growth factor A上市药物数量50
中文名称血管内皮生长因子A临床药物数量60
靶点别称Vascular Endothelial Growth Factor，VEGF-A，MVCD1，Vascular endothelial growth factor A，VEGF，VEGFA，VPF，Vascular Endothelial Growth Factor A165，Vascular permeability factor，Vascular Endothelial Growth Factor A121最高研发阶段批准上市
英文名称:Vascular endothelial growth factor A
中文名称血管内皮生长因子A
靶点别称Vascular Endothelial Growth Factor，VEGF-A，MVCD1，Vascular endothelial growth factor A，VEGF，VEGFA，VPF，Vascular Endothelial Growth Factor A165，Vascular permeability factor，Vascular Endothelial Growth Factor A121
上市药物数量50
临床药物数量60
最高研发阶段Approved

VEGF165产品列表

  • 属性

    Protein (7)Beads (1)Kits (1)

  • 产品库

    在线 (9)

  • 物种

    Human (9)

  • 标签

    Tag Free (4)His Tag (2)His Tag & Avi Tag (1)- (2)

  • 标记

    Unconjugated (4)Biotin-labeled (2)FITC Labeled (1)- (2)

共 9 项数据
  • 1

VEGF165分子背景

VEGF165 is the most abundant splice variant of VEGF-A. VEGF165 is produced by a number of cells including endothelial cells, macrophages and T cells. VEGF165 is involved in angiogenesis, vascular endothelial cell survival, growth, migration and vascular permeability. VEGF gene expression is induced by hypoxia, inflammatory cytokines and oncogenes. VEGF165 binds to heparan sulfate and is retained on the cell surface and in the extracellular matrix. VEGF165 binds to the receptor tyrosine kinases, VEGFR1 and VEGFR2. VEGF165 is the only splice variant that binds to co-receptors NRP-1 and NRP-2 that function to enhance VEGFR2 signaling. Binding of VEGF165 to VEGFR1 and VEGFR2 leads to activation of the PI3K/AKT, p38 MAPK, FAK and paxillin. VEGF plays a key role in tumor angiogenesis in many cancers.

VEGF165分子别名

RP1-261G23.1,MGC70609,MVCD1,VEGFA,VPF

产品评论

  • 21********qq.com 2026-05-27
    0人点赞
    Human VEGF165 Protein, His Tag, low endotoxin (MALS verified)
    已经多次回购该货号VEGF165重组蛋白了，现货产品，用起来太方便了，省时省心。用前期剩余的蛋白一起平行检测了蛋白活力，ELISA数据一致性非常棒，值得回购。
  • 25********qq.com 2026-05-15
    1人点赞
    Human VEGF165 Protein, His Tag, low endotoxin (MALS verified)
    ACRO的这款VEGF165重组蛋白真是太好用了，本次回购主要用其做为抗原蛋白进行铺板筛选纳米抗体分子，不仅蛋白活性稳定，铺板效果依然很棒。选择购买ACRO质量稳定的现货蛋白，省时省成本。
  • 2026-05-12
    1人点赞
    Human VEGF165 Protein, His Tag, low endotoxin (MALS verified)
    购买该蛋白用于细胞增殖实验；实验数据稳定、重复性良好。产品靶点特异性强，无明显非特异反应；蛋白的内毒素控制优异，值得购买
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