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VCAM-1

VCAM-1信息

英文名称:Vascular cell adhesion molecule 1上市药物数量2
中文名称血管细胞粘附分子1临床药物数量1
靶点别称VCAM1，Vascular cell adhesion protein 1，V-CAM 1，CD106，Vascular Cell Adhesion Molecule 1，CD106 Antigen，INCAM-100，VCAM-1，Vascular Cell Adhesion Molecule-1最高研发阶段批准上市
英文名称:Vascular cell adhesion molecule 1
中文名称血管细胞粘附分子1
靶点别称VCAM1，Vascular cell adhesion protein 1，V-CAM 1，CD106，Vascular Cell Adhesion Molecule 1，CD106 Antigen，INCAM-100，VCAM-1，Vascular Cell Adhesion Molecule-1
上市药物数量2
临床药物数量1
最高研发阶段Approved

VCAM-1产品列表

  • 属性

    Protein (6)Cell Grade Beads (2)

  • 产品库

    在线 (8)

  • 物种

    Human (5)- (1)Cynomolgus (2)

  • 标签

    His Tag (2)Fc Tag (2)Fc Tag & Avi Tag (1)- (2)His Tag & Avi Tag (1)

  • 标记

    Unconjugated (4)Biotin-labeled (2) (2)

共 8 项数据
  • 1

VCAM-1分子背景

Vascular cell adhesion protein 1 (VCAM1) is also known as CD106, INCAM-100 and L1CAM, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. VCAM1 / CD106 contains 7 Ig-like C2-type (immunoglobulin-like) domains. CD106 / VCAM-1 is expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue. L1CAM / VCAM-1 is Important in cell-cell recognition and appears to function in leukocyte-endothelial cell adhesion. CD106 / VCAM1 interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1 / VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. INCAM-100 / VCAM1 binds to ECMV-D capsid proteins and acts as a receptor for this virus.

VCAM-1分子别名

VCAM1,CD106,INCAM-100,V-CAM 1,VCAM-1
  • 分子信息
  • 产品列表