TROP-2

TROP-2信息

英文名称:Tumor-associated calcium signal transducer 2上市药物数量3
中文名称肿瘤相关钙信号传感器2临床药物数量27
靶点别称Tumor-associated calcium signal transducer 2,M1S1,TROP2,TACSTD2,Pancreatic carcinoma marker protein GA733-1,Tumor Associated Calcium Signal Transducer 2,GA733-1,Membrane Component, Chromosome 1, Surface Marker 1,Gastrointestinal Tumor-Associated Antigen GA7331,Pancreatic Carcinoma Marker Protein GA7331,Cell surface glycoprotein Trop-2,Membrane component chromosome 1 surface marker 1,40kD Glycoprotein, Identified By Monoclonal Antibody GA733,Cell Surface Glycoprotein TROP2,Epithelial Glycoprotein-1,Truncated TACSTD2,GA7331,EGP-1,EGP1,GP50,Trophoblast Cell Surface Antigen 2最高研发阶段批准上市
英文名称:Tumor-associated calcium signal transducer 2
中文名称肿瘤相关钙信号传感器2
靶点别称Tumor-associated calcium signal transducer 2,M1S1,TROP2,TACSTD2,Pancreatic carcinoma marker protein GA733-1,Tumor Associated Calcium Signal Transducer 2,GA733-1,Membrane Component, Chromosome 1, Surface Marker 1,Gastrointestinal Tumor-Associated Antigen GA7331,Pancreatic Carcinoma Marker Protein GA7331,Cell surface glycoprotein Trop-2,Membrane component chromosome 1 surface marker 1,40kD Glycoprotein, Identified By Monoclonal Antibody GA733,Cell Surface Glycoprotein TROP2,Epithelial Glycoprotein-1,Truncated TACSTD2,GA7331,EGP-1,EGP1,GP50,Trophoblast Cell Surface Antigen 2
上市药物数量3
临床药物数量27
最高研发阶段Approved

TROP-2产品列表

  • 属性

    Protein (18)Beads (1)Cell (1)Antibody (1)Kits (1)

  • 产品库

    在线 (22)

  • 物种

    Human (10)Mouse (4)Rhesus macaque (4)Canine (1)Rabbit (1)Cynomolgus (2)

  • 标签

    His Tag (8)His Tag & Avi Tag (5)Fc Tag (2)- (4)Fc Tag & Avi Tag (3)

  • 标记

    Unconjugated (11)Biotin-labeled (8)- (3)

共 22 项数据
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TROP-2分子背景

TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.

TROP-2分子别名

TACSTD2,GA733-1,M1S1,TROP2

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产品评论

  • ga*******126.com 2026-02-13
    0人点赞
    已经多次回购该货号TROP-2重组蛋白了,本次回购该蛋白主要有用于检测抗体分子与该靶点蛋白的结合亲和力。蛋白纯度及活性均符合BLI检测要求,蛋白固化效果也是杠杠滴,检测数据稳定性好,KD数值准确可靠,值得回购。
  • 25********qq.com 2025-12-16
    0人点赞
    用来做小鼠TROP-2单抗筛选,直接把His-tag蛋白铺在ELISA板上,信噪比干净(背景 <0.05),阳性孔OD值达3.0。纯度和活性都很nice,两周就拿到了5株纳摩尔级亲和力克隆。省时间、省抗体,绝对是性价比最优之选。
  • 25********qq.com 2025-12-16
    0人点赞
    在TROP-2纳米抗体与全长抗体项目中,我们已多次回购ACRO该款重组蛋白。其核心优势在于卓越的批间一致性,不同批次产品的质检数据与功能活性(如结合实验)高度稳定,确保了研发数据的连贯与可比性。同时,蛋白纯度高、活性好,为筛选与表征提供了可靠基础。重复验证成本显著降低,强烈推荐。
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