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TREM-1

TREM-1信息

英文名称:Triggering receptor expressed on myeloid cells 1上市药物数量0
中文名称髓系细胞表达的触发受体-1临床药物数量5
靶点别称Triggering Receptor Expressed On Myeloid Cells 1，CD354 Antigen，Triggering Receptor Expressed on Myeloid Cells-1，TREM-1，TREM1，CD354，Triggering receptor expressed on monocytes 1最高研发阶段临床二期
英文名称:Triggering receptor expressed on myeloid cells 1
中文名称髓系细胞表达的触发受体-1
靶点别称Triggering Receptor Expressed On Myeloid Cells 1，CD354 Antigen，Triggering Receptor Expressed on Myeloid Cells-1，TREM-1，TREM1，CD354，Triggering receptor expressed on monocytes 1
上市药物数量0
临床药物数量5
最高研发阶段Phase 2 Clinical

TREM-1产品列表

  • 属性

    Protein (1)

  • 产品库

    在线 (1)

  • 物种

    Human (1)

  • 标签

    Fc Tag (1)

  • 标记

    Unconjugated (1)

共 1 项数据
  • 1

TREM-1分子背景

Triggering receptor expressed on myeloid cells 1 (TREM1) is also known as CD antigen CD354, and is a type I transmembrane protein with a single Ig-like domain. TREM1 is highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. TREM-1 / CD354 stimulates neutrophil and monocyte-mediated inflammatory responses, and also triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. TREM1 can interacts with TYROBP / DAP12.

TREM-1分子别名

TREM1,CD354

产品评论

  • wa***sphchina.com 2025-07-29
    0人点赞
    Human TREM-1 / CD354 Protein, Fc Tag
    ACRO公司的服务非常好，下单后蛋白一般都会在两三天收到货，这次购买了TR1-H5251商品，经过ELISA检测后结果表明还重组蛋白活性良好，可以用于后期的实验，非常赞！
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