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TNFR1

TNFR1信息

英文名称:Tumor necrosis factor receptor superfamily member 1A上市药物数量0
中文名称肿瘤坏死因子受体1型临床药物数量2
靶点别称Tumor necrosis factor receptor 1，TNF-R1，Tumor necrosis factor receptor type I，TNF-RI，TNFR-I，CD120a，TNF Receptor Superfamily Member 1A，TNFAR，Tumor Necrosis Factor Receptor Superfamily Member 1A，TNF-R-I，TNF-R55，TNFR60，TNF-R，TNFR1，Tumor Necrosis Factor Receptor Superfamily， Member 1A，Tumor Necrosis Factor Receptor 1A Isoform Beta，Tumor Necrosis Factor Binding Protein 1，Tumor Necrosis Factor Receptor Type 1，Tumor Necrosis Factor Receptor Type I，Tumor Necrosis Factor-Alpha Receptor，Tumor Necrosis Factor Receptor 1，CD120a Antigen，TNFRSF1A，TNFR55，P55-R，TBP1，FPF，TBPI，p55，p60最高研发阶段临床三期
英文名称:Tumor necrosis factor receptor superfamily member 1A
中文名称肿瘤坏死因子受体1型
靶点别称Tumor necrosis factor receptor 1，TNF-R1，Tumor necrosis factor receptor type I，TNF-RI，TNFR-I，CD120a，TNF Receptor Superfamily Member 1A，TNFAR，Tumor Necrosis Factor Receptor Superfamily Member 1A，TNF-R-I，TNF-R55，TNFR60，TNF-R，TNFR1，Tumor Necrosis Factor Receptor Superfamily， Member 1A，Tumor Necrosis Factor Receptor 1A Isoform Beta，Tumor Necrosis Factor Binding Protein 1，Tumor Necrosis Factor Receptor Type 1，Tumor Necrosis Factor Receptor Type I，Tumor Necrosis Factor-Alpha Receptor，Tumor Necrosis Factor Receptor 1，CD120a Antigen，TNFRSF1A，TNFR55，P55-R，TBP1，FPF，TBPI，p55，p60
上市药物数量0
临床药物数量2
最高研发阶段Phase 3 Clinical

TNFR1产品列表

  • 属性

    Protein (8)

  • 产品库

    在线 (8)

  • 物种

    Human (5)Human & Mouse (2)Porcine (1)

  • 标签

    His Tag (3)Fc Tag (1)Fc Tag & Avi Tag (1)His Tag & Avi Tag (3)

  • 标记

    Unconjugated (4)Biotin-labeled (4)

共 8 项数据
  • 1

TNFR1分子背景

Tumor necrosis factor receptor 1 (TNF-R1) is also known as Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A), TNFAR, CD antigen CD120a, which belongs to the tumor necrosis factor receptor superfamily. TNF-R1 contains one death domain and four TNFR-Cys repeats. TNF-R1 is the receptor of TNFSF2 / TNF-alpha and homotrimeric TNFSF1 / lymphotoxin - alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. TNF-R1 contributes to the induction of non - cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. Defects in TNFRSF1A are the cause of familial hibernian fever (FHF).

TNFR1分子别名

TNFR1,CD120a,TNFRSF1A,FPF,TBP1,TNF-R,TNF-R-I,TNF-R55,TNFAR,TNFR55,TNFR60,p55,p60

产品评论

  • tm*****sina.cn 2025-12-26
    0人点赞
    Human TNFR1 / CD120a / TNFRSF1A Protein, His Tag
    Acro这个TNF 超家族的蛋白生产的很好用，我们包被好这个蛋白用来做ELISA实验，采用配体TNF-a作为阳性对照进行结合实验，同时加测自己纯化的蛋白片段。都表现了很强的结合能力。而且Acro加发货快，每次都不耽误实验进程。
  • 18********qq.com 2025-05-20
    2人点赞
    Human TNFR1 / CD120a / TNFRSF1A Protein, Fc Tag (MALS verified)
    特别实惠的一款Human TNFR1重组蛋白，选择该蛋白主要用于动物的免疫，蛋白纯度，内毒素水平均符合免疫要求，活性很稳定，三免后的血清效价已经很明显了，四免后成功拿到了高质量抗体库，愿筛选顺利。
  • ga*******126.com 2025-04-24
    1人点赞
    Human TNFR1 / CD120a / TNFRSF1A Protein, Fc Tag (MALS verified)
    使用该重组蛋白，主要用于噬菌体展示抗体库的筛选，蛋白活性很不错，通过3轮负筛和正筛后成功拿到了高特异性高亲和力突变抗体序列，后期还会回购用于进一步抗体活性检测。
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