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TNF-alpha

TNF-alpha信息

英文名称:Tumor necrosis factor α上市药物数量64
中文名称肿瘤坏死因子α临床药物数量58
靶点别称ICD1，Tumor necrosis factor，Tumor Necrosis Factor (TNF Superfamily， Member 2)，Tumor Necrosis Factor Ligand 1F，Tumor Necrosis Factor-Alpha，TNF Superfamily， Member 2，TNF， Macrophage-Derived，TNF， Monocyte-Derived，APC1 Protein，TNLG1F，DIF，NTF，TNF-a，TNF-alpha，ICD2，N-terminal fragment，TNF，Tumor necrosis factor ligand superfamily member 2，Cachectin，TNFSF2，TNFA最高研发阶段批准上市
英文名称:Tumor necrosis factor α
中文名称肿瘤坏死因子α
靶点别称ICD1，Tumor necrosis factor，Tumor Necrosis Factor (TNF Superfamily， Member 2)，Tumor Necrosis Factor Ligand 1F，Tumor Necrosis Factor-Alpha，TNF Superfamily， Member 2，TNF， Macrophage-Derived，TNF， Monocyte-Derived，APC1 Protein，TNLG1F，DIF，NTF，TNF-a，TNF-alpha，ICD2，N-terminal fragment，TNF，Tumor necrosis factor ligand superfamily member 2，Cachectin，TNFSF2，TNFA
上市药物数量64
临床药物数量58
最高研发阶段Approved

TNF-alpha产品列表

  • 属性

    Protein (12)Kits (10)Antibody (6)

  • 产品库

    在线 (28)

  • 物种

    Human (16)Mouse (10)Canine (1)Cynomolgus (1)

  • 标签

    His Tag & Avi Tag (2)Tag Free (3)His Tag (4)- (10)Mouse IgG1 (2)Human IgG1 (4)Fc Tag (2)Fc Tag & Avi Tag (1)

  • 标记

    Biotin-labeled (5)Unconjugated (12)- (2) (7)HRP Labeled (1)PE Labeled (1)

共 28 项数据
  • 1
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TNF-alpha分子背景

Tumor necrosis factor alpha (TNFα) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFα is in the regulation of immune cells. TNFα is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFα production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer. Recombinant TNFα is used as an immunostimulant under the INN tasonermin. TNFα can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.

TNF-alpha分子别名

DIF,TNF-alpha,TNFA,TNFSF2,cachexin,cachectin,TNFα

产品评论

  • 22********qq.com 2025-05-27
    0人点赞
    Mouse TNF-alpha Protein, His Tag
    ACRO的蛋白质控严格，质量一直很稳定。提供的COA详实，保存条件明确。发货及时，物流高效，为项目进程节省了大把时间。客服专业，能快速响应并解决技术难题。每次回购都很满意，值得点赞。
  • 22********qq.com 2025-05-27
    0人点赞
    Biotinylated Human TNF-alpha Protein, His,Avitag™, active trimer (MALS verified)
    采购ACRO的human TNF-alpha抗原重组蛋白，主要用于抗体亲和力成熟筛选项目，通过几轮蛋白固相筛选，成功筛到了亲和力明显高于母本抗体的突变体克隆，蛋白活性很稳定，还会购买其他种属的蛋白进一步开展交叉筛选。
  • 18********qq.com 2025-05-20
    0人点赞
    Mouse TNF-alpha Protein, His Tag
    最近使用Mouse TNF-alpha蛋白，针对噬菌体展示环肽库进行了生物淘筛，蛋白特异性强，灵敏度高，筛选富集明显，测序结果显示富集库多样性也很高，结果超出预期，ACRO蛋白质量值得信赖。
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