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TNF-alpha

TNF-alpha信息

英文名称:Tumor necrosis factor α上市药物数量64
中文名称肿瘤坏死因子α临床药物数量58
靶点别称ICD1，Tumor necrosis factor，Tumor Necrosis Factor (TNF Superfamily， Member 2)，Tumor Necrosis Factor Ligand 1F，Tumor Necrosis Factor-Alpha，TNF Superfamily， Member 2，TNF， Macrophage-Derived，TNF， Monocyte-Derived，APC1 Protein，TNLG1F，DIF，NTF，TNF-a，TNF-alpha，ICD2，N-terminal fragment，TNF，Tumor necrosis factor ligand superfamily member 2，Cachectin，TNFSF2，TNFA最高研发阶段批准上市
英文名称:Tumor necrosis factor α
中文名称肿瘤坏死因子α
靶点别称ICD1，Tumor necrosis factor，Tumor Necrosis Factor (TNF Superfamily， Member 2)，Tumor Necrosis Factor Ligand 1F，Tumor Necrosis Factor-Alpha，TNF Superfamily， Member 2，TNF， Macrophage-Derived，TNF， Monocyte-Derived，APC1 Protein，TNLG1F，DIF，NTF，TNF-a，TNF-alpha，ICD2，N-terminal fragment，TNF，Tumor necrosis factor ligand superfamily member 2，Cachectin，TNFSF2，TNFA
上市药物数量64
临床药物数量58
最高研发阶段Approved

TNF-alpha产品列表

  • 属性

    Protein (17)Kits (11)Antibody (4)Cell (1)

  • 产品库

    在线 (33)

  • 物种

    Human (19)Mouse (9)Canine (1)Cynomolgus (2)Rat (1)Rabbit (1)

  • 标签

    His Tag & Avi Tag (3)Tag Free (5)His Tag (6)- (12)Mouse IgG1 (1)Human IgG1 (3)Fc Tag (2)Fc Tag & Avi Tag (1)

  • 标记

    Biotin-labeled (6)Unconjugated (15)- (12)

共 33 项数据
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TNF-alpha分子背景

Tumor necrosis factor alpha (TNFα) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFα is in the regulation of immune cells. TNFα is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFα production has been implicated in a variety of human diseases, including major depression, Alzheimers disease and cancer. Recombinant TNFα is used as an immunostimulant under the INN tasonermin. TNFα can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.

TNF-alpha分子别名

DIF,TNF-alpha,TNFA,TNFSF2,cachexin,cachectin,TNFα

产品评论

  • 2026-05-11
    0人点赞
    Human TNF-alpha Protein, His Tag, active trimer, low endotoxin (MALS verified)
    我们是做一些检测的实验，可以说ACRO家的这款蛋白质量真的没得说，对我们的检测提高了很大的效率，最后也拿到了一个满意的结果，我们团队所有人都一致称赞ACRO家的东西，用着让人放心，点赞👍
  • ll*****aptbiotech.com 2026-04-09
    0人点赞
    Biotinylated Human TNF-alpha Protein, His,Avitag™, active trimer (MALS verified)
    百普赛斯家的TNA-H82E3实验效果显示复溶后溶液澄清。做 ELISA 或 BLI 时，与 TNFR1/2 及阿达木单抗结合信号强，线性范围宽（0.1–10 ng/mL），背景干净，数据重复性高。 跟据图谱的反馈SDS-PAGE 条带单一（>95% 纯度），SEC-MALS 显示为均一三聚体，图谱标准无杂带，符合高端试剂要求。
  • tm*****sina.cn 2025-12-29
    0人点赞
    Human TNF-alpha Protein, His Tag, active trimer, low endotoxin (MALS verified)
    购买Human TNF-alpha Protein, His Tag, active trimer重组蛋白主要用于SPR亲和力检测的实验，实验结果显示，coat的TNF-a蛋白很不错，和抗体的结合达到了nM级别。Acro家的顺丰物流很快，保证了实验进度。
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