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Thrombopoietin R

Thrombopoietin R信息

英文名称:Thrombopoietin receptor上市药物数量8
中文名称血小板生成素受体临床药物数量11
靶点别称CD110 Antigen，THCYT2，C-MPL，CD110，MPLV，Receptors， Thrombopoietin，MPL，TPOR，Myeloproliferative leukemia protein，Myeloproliferative Leukemia Virus Oncogene，Proto-Oncogene C-Mpl，TPO-R，MPL Proto-Oncogene， Thrombopoietin Receptor，Thrombopoietin Receptor，THPOR最高研发阶段批准上市
英文名称:Thrombopoietin receptor
中文名称血小板生成素受体
靶点别称CD110 Antigen，THCYT2，C-MPL，CD110，MPLV，Receptors， Thrombopoietin，MPL，TPOR，Myeloproliferative leukemia protein，Myeloproliferative Leukemia Virus Oncogene，Proto-Oncogene C-Mpl，TPO-R，MPL Proto-Oncogene， Thrombopoietin Receptor，Thrombopoietin Receptor，THPOR
上市药物数量8
临床药物数量11
最高研发阶段Approved

Thrombopoietin R产品列表

  • 属性

    Protein (11)

  • 产品库

    在线 (11)

  • 物种

    Human (1)Mouse (3)Cynomolgus (2)Rabbit (2)Porcine (2)Rat (1)

  • 标签

    His Tag (6)His Tag & Avi Tag (5)

  • 标记

    Unconjugated (6)Biotin-labeled (5)

共 11 项数据
  • 1
  • 2

Thrombopoietin R分子背景

Thrombopoietin R, also known as TPO-R, is expressed predominantly on the surface of MKs, platelets, hemangioblasts, and hematopoietic stem cells (HSCs). Binding of TPO to the megakaryocyte TPO-R leads to different effects: prevention of megakaryocyte apoptosis; increased megakaryocyte number, size, and ploidy; increasing rate of megakaryocyte maturation; and internalization of the TPO/TPO-R complex. Thrombopoietin R involved in multiple signal transduction pathways, such as JAK, STAT, and MAP kinase.

Thrombopoietin R分子别名

MPL,C-MPL,CD110,MPLV,THCYT2,TPOR
  • 分子信息
  • 产品列表