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Stathmin 1

Stathmin 1信息

英文名称:Stathmin上市药物数量0
中文名称Stathmin蛋白临床药物数量2
靶点别称Protein Pr22，Phosphoprotein p19，LAP18，C1orf215，STMN1，Stathmin 1，Oncoprotein 18，Leukemia-Associated Phosphoprotein P18，Stathmin 1/Oncoprotein 18，Metablastin，Prosolin，Chromosome 1 Open Reading Frame 215，Testicular Tissue Protein Li 189，Transmembrane Protein C1orf215，Phosphoprotein 19，Stathmin，PP17，PR22，Op18，Pp19，Lag，SMN，FLJ32206最高研发阶段临床一期
英文名称:Stathmin
中文名称Stathmin蛋白
靶点别称Protein Pr22，Phosphoprotein p19，LAP18，C1orf215，STMN1，Stathmin 1，Oncoprotein 18，Leukemia-Associated Phosphoprotein P18，Stathmin 1/Oncoprotein 18，Metablastin，Prosolin，Chromosome 1 Open Reading Frame 215，Testicular Tissue Protein Li 189，Transmembrane Protein C1orf215，Phosphoprotein 19，Stathmin，PP17，PR22，Op18，Pp19，Lag，SMN，FLJ32206
上市药物数量0
临床药物数量2
最高研发阶段Phase 1 Clinical

Stathmin 1产品列表

  • 属性

    Protein (1)

  • 产品库

    在线 (1)

  • 物种

    Human (1)

  • 标签

    His Tag (1)

  • 标记

    Unconjugated (1)

共 1 项数据
  • 1

Stathmin 1分子背景

Stathmin (STMN1), a member of the stathmin family, is also known as Leukemia-associated phosphoprotein p18, Oncoprotein 18 (Op18), Phosphoprotein p19 (pp19), Protein Pr22 and pp17, which contains one SLD (stathmin-like) domain. The function of STMN1 as an important regulatory protein of microtubule dynamics has been well-characterized. Stathmin (STMN1) interacts with two molecules of dimeric α,β-tubulin to form a tight ternary complex called the T2S complex.One mole of STMN1 binds to two moles of tubulin dimers through the stathmin-like domain (SLD).When STMN1 sequesters tubulin into the T2S complex, tubulin becomes non-polymerizable. Without tubulin polymerization, there is no microtubule assembly.STMN1 also promotes microtubule disassembly by acting directly on the microtubule ends.

Stathmin 1分子别名

STMN1,Stathmin,C1orf215,LAP18,OP18
  • 分子信息
  • 产品列表