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Serpin F1

Serpin F1信息

英文名称:Pigment epithelium-derived factor上市药物数量0
中文名称色素上皮衍生因子临床药物数量2
靶点别称Cell proliferation-inducing gene 35 protein，EPC-1，Serpin Family F Member 1，Proliferation-Inducing Protein 35，OI12，Serpin Peptidase Inhibitor， Clade F (Alpha-2 Antiplasmin， Pigment Epithelium Derived Factor)， Member 1，PIG35，Serine (Or Cysteine) Proteinase Inhibitor， Clade F (Alpha-2 Antiplasmin， Pigment Epithelium Derived Factor)， Member 1，OI6，Testis Tissue Sperm-Binding Protein Li 70n，SERPINF1，Serpin F1最高研发阶段临床三期
英文名称:Pigment epithelium-derived factor
中文名称色素上皮衍生因子
靶点别称Cell proliferation-inducing gene 35 protein，EPC-1，Serpin Family F Member 1，Proliferation-Inducing Protein 35，OI12，Serpin Peptidase Inhibitor， Clade F (Alpha-2 Antiplasmin， Pigment Epithelium Derived Factor)， Member 1，PIG35，Serine (Or Cysteine) Proteinase Inhibitor， Clade F (Alpha-2 Antiplasmin， Pigment Epithelium Derived Factor)， Member 1，OI6，Testis Tissue Sperm-Binding Protein Li 70n，SERPINF1，Serpin F1
上市药物数量0
临床药物数量2
最高研发阶段Phase 3 Clinical

Serpin F1产品列表

  • 属性

    Protein (1)

  • 产品库

    在线 (1)

  • 物种

    Human (1)

  • 标签

    His Tag (1)

  • 标记

    Unconjugated (1)

共 1 项数据
  • 1

Serpin F1分子背景

erpin F1 (SERPINF1) is also known as Pigment epithelium-derived factor (PEDF), Cell proliferation-inducing gene 35 protein (PIG35). Serpin F1 belongs to the serpin family. Serpin F1 is expressed in quiescent cells. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. Endothelial cell migration is inhibited by SERPINF1/ PEDF. PEDF / SERPINF1 suppresses retinal neovascularization and endothelial cell proliferation. PEDF is also responsible for apoptosis of endothelial cells either through the p38 MAPK pathway or through the FAS/FASL pathway. PEDF also displays neurotrophic functions.

Serpin F1分子别名

SERPINF1,Serpin F1,PEDF,PIG35,EPC-1
  • 分子信息
  • 产品列表