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PD-L1

PD-L1信息

英文名称:Programmed death-ligand 1上市药物数量12
中文名称程序性死亡配体1临床药物数量153
靶点别称HPD-L1，Programmed Cell Death 1 Ligand 1，PDCD1L1，B7H1，PDL1，Programmed Death Ligand 1，B7-H1，B7-H，B7-H1 Antigen，CD274，B7 homolog 1，PDCD1 ligand 1，PD-L1，PDCD1LG1，CD274 Molecule，CD274 Antigen最高研发阶段批准上市
英文名称:Programmed death-ligand 1
中文名称程序性死亡配体1
靶点别称HPD-L1，Programmed Cell Death 1 Ligand 1，PDCD1L1，B7H1，PDL1，Programmed Death Ligand 1，B7-H1，B7-H，B7-H1 Antigen，CD274，B7 homolog 1，PDCD1 ligand 1，PD-L1，PDCD1LG1，CD274 Molecule，CD274 Antigen
上市药物数量12
临床药物数量153
最高研发阶段Approved

PD-L1产品列表

  • 属性

    Protein (27)Cell (5)Kits (3)Antibody (1)

  • 产品库

    在线 (36)

  • 物种

    Human (20)Mouse (6)Cynomolgus / Rhesus macaque (4)Rabbit (3)Canine (2)Feline (1)

  • 标签

    His Tag & Avi Tag (4)His Tag & Fc Tag & Avi Tag (1)Fc Tag & Avi Tag (3)His Tag (8)Fc Tag (5)Mouse IgG Fc Tag (2)Strep Tag (1)Llama IgG Fc Tag (1)GFP Tag (1)Mouse IgG Fc Tag & Avi Tag (1)- (8)Tag Free (1)

  • 标记

    Biotin-labeled (9)Unconjugated (19)- (7)PE Labeled (1)

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PD-L1分子背景

Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.

PD-L1分子别名

PD-L1,CD274,B7-H1,PDCD1L1,PDCD1LG1

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