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Neuropilin-1

Neuropilin-1信息

英文名称:Neuropilin-1上市药物数量0
中文名称神经毡蛋白-1临床药物数量3
靶点别称BDCA4，NP1，Neuropilin-1，NRP1，CD304，VEGF165R，Neuropilin 1，Vascular Endothelial Cell Growth Factor 165 Receptor，NRP，Transmembrane Receptor，CD304 Antigen最高研发阶段临床二期
英文名称:Neuropilin-1
中文名称神经毡蛋白-1
靶点别称BDCA4，NP1，Neuropilin-1，NRP1，CD304，VEGF165R，Neuropilin 1，Vascular Endothelial Cell Growth Factor 165 Receptor，NRP，Transmembrane Receptor，CD304 Antigen
上市药物数量0
临床药物数量3
最高研发阶段Phase 2 Clinical

Neuropilin-1产品列表

  • 属性

    Protein (6)

  • 产品库

    在线 (6)

  • 物种

    Human (4)Mouse (2)

  • 标签

    His Tag (2)Fc Tag (1)His Tag & Avi Tag (1)Mouse IgG Fc Tag (2)

  • 标记

    Unconjugated (5)Biotin-labeled (1)

共 6 项数据
  • 1

Neuropilin-1分子背景

Neuropilin-1 (NRP1) is also known as Vascular endothelial cell growth factor 165 receptor (VEGF165R), CD antigen CD304, which belongs to the neuropilin family. The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells.

Neuropilin-1分子别名

NRP1,Neuropilin-1,NRP,VEGF165R,CD304
  • 分子信息
  • 产品列表