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MIF

MIF信息

英文名称:Macrophage migration inhibitory factor上市药物数量1
中文名称巨噬细胞移动抑制因子临床药物数量3
靶点别称EC:5.3.2.1，GIF，EC 5.3.3.12，EC 5.3.2.1，Macrophage Migration-Inhibitory Factors，Epididymis Secretory Sperm Binding Protein，EC:5.3.3.12，Phenylpyruvate Tautomerase，L-Dopachrome Tautomerase，MMIF，Glycosylation-inhibiting factor，L-dopachrome isomerase，MIF，Macrophage Migration Inhibitory Factor，Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor)，GLIF最高研发阶段批准上市
英文名称:Macrophage migration inhibitory factor
中文名称巨噬细胞移动抑制因子
靶点别称EC:5.3.2.1，GIF，EC 5.3.3.12，EC 5.3.2.1，Macrophage Migration-Inhibitory Factors，Epididymis Secretory Sperm Binding Protein，EC:5.3.3.12，Phenylpyruvate Tautomerase，L-Dopachrome Tautomerase，MMIF，Glycosylation-inhibiting factor，L-dopachrome isomerase，MIF，Macrophage Migration Inhibitory Factor，Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor)，GLIF
上市药物数量1
临床药物数量3
最高研发阶段Approved

MIF产品列表

  • 属性

    Protein (1)

  • 产品库

    在线 (1)

  • 物种

    Human (1)

  • 标签

    His Tag & Avi Tag (1)

  • 标记

    Biotin-labeled (1)

共 1 项数据
  • 1

MIF分子背景

Macrophage migration inhibitory factor(MIF) is also known as Glycosylation-inhibiting factor(GIF), L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase. Interacts with CXCR2 extracellular domain, CD74 extracellular domain, COPS5 and BNIPL. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.

MIF分子别名

MIF,GLIF,MMIF,GIF
  • 分子信息
  • 产品列表