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LILRB1

LILRB1信息

英文名称:Leukocyte immunoglobulin-like receptor B1上市药物数量0
中文名称白细胞免疫球蛋白样受体B1临床药物数量6
靶点别称Leukocyte Immunoglobulin Like Receptor B1，LIR-1，MIR-7，ILT2，LIR1，Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1 Soluble Isoform，PIR-B，Leukocyte immunoglobulin-like receptor 1，MIR7，PIRB，CD85j，Immunoglobulin-like transcript 2，Leukocyte Immunoglobulin-Like Receptor， Subfamily B (With TM And ITIM Domains)， Member 1，Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1，Monocyte/Macrophage Immunoglobulin-Like Receptor 7，CD85 Antigen-Like Family Member J，Myeloid Inhibitory Receptor 7，Leucocyte Ig-Like Receptor B1，ILT-2，CD85j Antigen，Ig-Like Transcript 2最高研发阶段临床二期
英文名称:Leukocyte immunoglobulin-like receptor B1
中文名称白细胞免疫球蛋白样受体B1
靶点别称Leukocyte Immunoglobulin Like Receptor B1，LIR-1，MIR-7，ILT2，LIR1，Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1 Soluble Isoform，PIR-B，Leukocyte immunoglobulin-like receptor 1，MIR7，PIRB，CD85j，Immunoglobulin-like transcript 2，Leukocyte Immunoglobulin-Like Receptor， Subfamily B (With TM And ITIM Domains)， Member 1，Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1，Monocyte/Macrophage Immunoglobulin-Like Receptor 7，CD85 Antigen-Like Family Member J，Myeloid Inhibitory Receptor 7，Leucocyte Ig-Like Receptor B1，ILT-2，CD85j Antigen，Ig-Like Transcript 2
上市药物数量0
临床药物数量6
最高研发阶段Phase 2 Clinical

LILRB1产品列表

  • 属性

    Protein (7)

  • 产品库

    在线 (7)

  • 物种

    Human (6)Cynomolgus (1)

  • 标签

    Fc Tag (1)Fc Tag & Avi Tag (2)His Tag (3)His Tag & Avi Tag (1)

  • 标记

    Unconjugated (4)Biotin-labeled (3)

共 7 项数据
  • 1

LILRB1分子背景

CD85 antigen-like family member J (CD85J) is also known as Leukocyte immunoglobulin-like receptor subfamily B member 1 (LILRB1 or LIR-1), Immunoglobulin-like transcript 2 (ILT-2), Monocyte/macrophage immunoglobulin-like receptor 7 (MIR7), which belongs to leukocyte immunoglobulin-like receptor (LIR) family. CD85J / LILRB1 Contains 4 Ig-like C2-type (immunoglobulin-like) domains. CD85J / LIR-1 is expressed predominantly on B-cells and monocytes. CD85J is receptor for class I MHC antigens and recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles and is also receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. CD85J / LILRB1 interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. CD85J / LILRB1 inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

LILRB1分子别名

CD85J,LILRB1,CD85,ILT2,LIR1,MIR7

产品评论

  • 13********qq.com 2022-12-09
    0人点赞
    Cynomolgus LILRB1 / CD85j / ILT2 Protein, His Tag
    这个我们主要用来筛选我们白介二的靶点，为了获得一些优选克隆，也用于一般的分子水平上的活性检测、结果还不错呢。
  • 13********qq.com 2022-12-09
    0人点赞
    Human LILRB1 / CD85j / ILT2 Protein, Fc Tag (MALS verified)
    这次购买的Acro产品，我们主要用来进行生物素标记，剩余部分用来进行Elisa实验，是我们比较信得过产品哦
  • 2022-04-20
    0人点赞
    Biotinylated Human LILRB1 / CD85j / ILT2 Protein, Fc,Avitag™
    This sample was highly pure which was very helpful in selection campaigns to find specific molecules. We did our own QC on the sample to verify purity and it matched up perfectly with SDS-PAGE and SEC-MALS that is provided on the website. Shipping was quick to prevent delays in our project timelines. This sample was sent lyophilized and very easy to reconstitute for use.
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