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LIGHT

LIGHT信息

英文名称:Tumor necrosis factor superfamily member 14上市药物数量0
中文名称肿瘤坏死因子超家族成员14临床药物数量1
靶点别称CD258 Antigen，Herpes Virus Entry Mediator Ligand，TNFSF14，Herpesvirus Entry Mediator Ligand，LIGHT，Tumor Necrosis Factor (Ligand) Superfamily， Member 14，CD258，HVEM-L，Tumor Necrosis Factor Ligand 1D，LTg，HVEML，TNF Superfamily Member 14，Tumor Necrosis Factor Ligand Superfamily Member 14，Tumor Necrosis Factor Superfamily Member 14最高研发阶段临床二期
英文名称:Tumor necrosis factor superfamily member 14
中文名称肿瘤坏死因子超家族成员14
靶点别称CD258 Antigen，Herpes Virus Entry Mediator Ligand，TNFSF14，Herpesvirus Entry Mediator Ligand，LIGHT，Tumor Necrosis Factor (Ligand) Superfamily， Member 14，CD258，HVEM-L，Tumor Necrosis Factor Ligand 1D，LTg，HVEML，TNF Superfamily Member 14，Tumor Necrosis Factor Ligand Superfamily Member 14，Tumor Necrosis Factor Superfamily Member 14
上市药物数量0
临床药物数量1
最高研发阶段Phase 2 Clinical

LIGHT产品列表

  • 属性

    Protein (6)Cell (1)

  • 产品库

    在线 (7)

  • 物种

    Human (5)Cynomolgus (1)Mouse (1)

  • 标签

    Mouse IgG Fc Tag (1)His Tag (4)Fc Tag (1)- (1)

  • 标记

    Unconjugated (6)- (1)

共 7 项数据
  • 1

LIGHT分子背景

Tumor necrosis factor ligand superfamily member 14(LIGHT) is a tumor necrosis factor (TNF) superfamily ligand that regulates T cell immune responses by signaling through the herpes virus entry mediator (HVEM) and the lymphotoxin beta receptor (LTbetaR). LIGHT has emerged as a potent initiator of T cell co-stimulation signals effecting CTL-mediated tumor rejection, allograft rejection and graft versus host disease. Constitutive expression of LIGHT leads to tissue destruction and autoimmune-like disease syndromes.

LIGHT分子别名

CD258 antigen,CD258,HVEM-L,LIGHT,LTg,TNFSF14,TR2,HVEML

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