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LGR5

LGR5信息

英文名称:Leucine-rich repeat-containing G-protein coupled receptor 5上市药物数量0
中文名称富含亮氨酸重复序列的G蛋白偶联受体-5临床药物数量2
靶点别称FEX，G Protein-Coupled Receptor 49，GRP49，HG38，G-protein coupled receptor HG38，GPR49，GPR67，G-protein coupled receptor 49，Leucine-rich repeat-containing G-protein coupled receptor 5，LGR5，Leucine Rich Repeat Containing G Protein-Coupled Receptor 5，G-Protein Coupled Receptor 67，Orphan G Protein-Coupled Receptor HG38最高研发阶段临床三期
英文名称:Leucine-rich repeat-containing G-protein coupled receptor 5
中文名称富含亮氨酸重复序列的G蛋白偶联受体-5
靶点别称FEX，G Protein-Coupled Receptor 49，GRP49，HG38，G-protein coupled receptor HG38，GPR49，GPR67，G-protein coupled receptor 49，Leucine-rich repeat-containing G-protein coupled receptor 5，LGR5，Leucine Rich Repeat Containing G Protein-Coupled Receptor 5，G-Protein Coupled Receptor 67，Orphan G Protein-Coupled Receptor HG38
上市药物数量0
临床药物数量2
最高研发阶段Phase 3 Clinical

LGR5产品列表

  • 属性

    Protein (4)

  • 产品库

    在线 (4)

  • 物种

    Human (3)Cynomolgus (1)

  • 标签

    His Tag (2)Fc Tag (1)His Tag & Avi Tag (1)

  • 标记

    Unconjugated (3)Biotin-labeled (1)

共 4 项数据
  • 1

LGR5分子背景

LGR5 (also known as GPR49) is a seven-transmembrane protein of the class A Rhodopsin-like family of GPCRs. LGR5 and LGR4 bind the R-spondins with high affinity and mediate the potentiation of Wnt/β-catenin signaling by enhancing Wnt-induced LRP6 phosphorylation. The LGR5/RSPO complex could promote Wnt signalling via the neutralization of two transmembrane E3 ligases, RNF43 and ZNRF3.

LGR5分子别名

LGR5, GPR49, GPR67, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, Leucine-rich repeat-containing G-protein coupled receptor 5

产品评论

  • 18********qq.com 2025-12-26
    0人点赞
    Human LGR5 / GPR49 protein, His Tag
    购买的Human LGR5蛋白主要用于筛选噬菌体展示抗体库，效果非常出色！蛋白纯度高、特异性强，活性稳定，能够有效捕获特异性结合的噬菌体克隆。在多轮淘选中表现出优异的稳定性和重复性，仅需微量（低至100 ng/孔）即可实现高效富集，显著提升阳性克隆的检出率。
  • 18********qq.com 2025-12-26
    0人点赞
    Cynomolgus LGR5 / GPR49 protein, His Tag
    人源与食蟹猴（Cynomolgus）LGR5蛋白具有高度同源性，因此本实验选用该货号的Cynomolgus LGR5蛋白主要用于阳性克隆的交叉活性ELISA检测。该蛋白具有高活性和高特异性，在仅使用100 ng/孔的包被量时，即可获得显著且可靠的OD值，值得回购。
  • 15********qq.com 2025-12-09
    0人点赞
    Human LGR5 / GPR49 protein, His Tag
    我们购买此蛋白主要用于噬菌体展示库的固相筛选实验。该蛋白带有Avi标签，灵敏度高且用量较少，低浓度铺板就足以获得很多高亲和阳性克隆。ACRO一直是我们的长期供应商，其蛋白产品值得信赖。
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