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Klotho beta

Klotho beta信息

英文名称:Klotho beta上市药物数量0
中文名称Klotho β蛋白临床药物数量3
靶点别称Klotho Beta，Klotho Beta-Like Protein，B-Klotho，Klotho Beta Like，Beta-Klotho，EC 3.2.1，BKL，BetaKlotho，KLB最高研发阶段临床二期
英文名称:Klotho beta
中文名称Klotho β蛋白
靶点别称Klotho Beta，Klotho Beta-Like Protein，B-Klotho，Klotho Beta Like，Beta-Klotho，EC 3.2.1，BKL，BetaKlotho，KLB
上市药物数量0
临床药物数量3
最高研发阶段Phase 2 Clinical

Klotho beta产品列表

  • 属性

    Protein (4)

  • 产品库

    在线 (4)

  • 物种

    Mouse (1)Cynomolgus / Rhesus macaque (1)Rat (1)Human (1)

  • 标签

    His Tag (4)

  • 标记

    Unconjugated (4)

共 4 项数据
  • 1

Klotho beta分子背景

KLB (Klotho Beta) is a Protein Coding gene. Among its related pathways are RET signaling and HIV Life Cycle. GO annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl compounds and fibroblast growth factor binding. An important paralog of this gene is KL. Klotho Beta is a regulator in multiple metabolic processes, while its role in cancer remains unclear. We found the expression of βKlotho was down-regulated in human hepatocellular carcinoma tissues compared with that in paired adjacent non-tumourous liver tissues. Hepatoma cells also showed decreased expression of βKlotho compared with normal hepatocyte cells. Reintroduction of βKlotho into hepatoma cells inhibited their proliferation.

Klotho beta分子别名

betaKlotho,beta-klotho,BKL,KLB,klotho beta like,klotho beta-like protein
  • 分子信息
  • 产品列表