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IL-33

IL-33信息

英文名称:Interleukin-33上市药物数量0
中文名称白细胞介素-33临床药物数量10
靶点别称Nuclear Factor For High Endothelial Venules，DVS27-Related Protein，IL1F11，IL33，Interleukin-1 family member 11，IL-1F11，Interleukin 33，Nuclear Factor From High Endothelial Venules，C9orf26，NF-HEV，Chromosome 9 Open Reading Frame 26 (NF-HEV)，Interleukin-1 Family， Member 11，NFEHEV，DVS27，IL-33，NFHEV，Interleukin-33，DKFZp586H0523最高研发阶段临床三期
英文名称:Interleukin-33
中文名称白细胞介素-33
靶点别称Nuclear Factor For High Endothelial Venules，DVS27-Related Protein，IL1F11，IL33，Interleukin-1 family member 11，IL-1F11，Interleukin 33，Nuclear Factor From High Endothelial Venules，C9orf26，NF-HEV，Chromosome 9 Open Reading Frame 26 (NF-HEV)，Interleukin-1 Family， Member 11，NFEHEV，DVS27，IL-33，NFHEV，Interleukin-33，DKFZp586H0523
上市药物数量0
临床药物数量10
最高研发阶段Phase 3 Clinical

IL-33产品列表

  • 属性

    Protein (11)

  • 产品库

    在线 (11)

  • 物种

    Human (6)Cynomolgus (3)Mouse (2)

  • 标签

    His Tag (6)His Tag & Avi Tag (5)

  • 标记

    Unconjugated (6)Biotin-labeled (5)

共 11 项数据
  • 1
  • 2

IL-33分子背景

Interleukin 33 (IL33) is known as C9orf26, DKFZp586H0523, DVS27, NF-HEV, NFEHEV, RP11-575C20.2,and is a cytokine belonging to the IL-1 superfamily. IL-33 induces helper T cells, mast cells, eosinophils and basophils to produce type 2 cytokines. IL-33 mediates its biological effects by interacting with the receptors ST2 (aka IL1RL1) and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines (e.g. IL-5 and IL-13) from polarized Th2 cells. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs.

IL-33分子别名

IL33,DV27,C9ORF26,IL1F11,NFHEV,DKFZp586H0523,DVS27,NFEHEV,RP11-575C20.2

产品评论

  • 18********qq.com 2025-12-26
    0人点赞
    Human IL-33 Protein, His Tag (HPLC verified)
    用这款IL-33蛋白建立实验方法非常顺利，结果完全符合预期。无论是ELISA检测、流式检测还是BLI/竞争实验，它都表现出了极佳的活性和稳定性。数据漂亮，重复性好，大大加速了项目研发进程。因为好用，我们已经多次回购，ACRO是我们值得信赖的长期合作伙伴。
  • 25********qq.com 2025-10-23
    0人点赞
    Mouse IL-33 Protein, His Tag
    购买该蛋白主要用于抗体蛋白分子种属交叉活性的ELISA检测，蛋白特异性强，高亲和力，每次重复实验数据一致性也特别好，物流速度很快，每次购买第三天就能拿到活性验证数据。
  • 22********qq.com 2025-10-22
    0人点赞
    Human IL-33 Protein, His Tag (HPLC verified)
    同时采购了人源和猴源不同种属的IL-33重组蛋白，主要用于候选抗体分子的亲和力检测，两种蛋白都适合BLI检测法进行检测，蛋白固化效果理想，获得的KD数据完全符合预期。
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